Results 101 to 110 of about 41,160 (242)

Leading the Loop: Anchor‐Led Orchestration in Nascent Circular Ecosystems—A Qualitative Case Study

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition towards a circular economy necessitates coordinated, systemic change across value chains. Yet the role of anchor firms in initiating and orchestrating nascent circular ecosystems remains underexplored. Using an inductive, qualitative single‐case design, we analyse a German mid‐sized entrepreneurial firm, drawing on 21 interviews
Johann Felix Mader, Patrick Spieth
wiley   +1 more source

Exploring Sustainable Growth: Eco‐Innovation Among Small and Medium‐Sized Enterprises

Business Strategy and the Environment, EarlyView.
ABSTRACT We examined how small and medium‐sized enterprises (SMEs) in the aerospace industry developed capabilities for eco‐innovation, specifically SMEs enrolled in a green transition mentorship programme. To this end, we conducted multiple case studies over 2 years (August 2022 to November 2024) to gather data through semi‐structured interviews with ...
Coralie Gagné, Sophie Veilleux, Fabiano Armellini, Carole Lalonde, Elicia Maine, Catherine Beaudry   +5 more
wiley   +1 more source

Precision Chemistry for Protein Lysine Modification

Chemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Disentangling Sex Differences in Sulfonylurea Drug Response With Genome‐Wide Association Studies in Individuals With Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
A sex‐stratified genome‐wide association study of sulfonylurea response identified sex‐specific genetic loci associated with HbA1c reduction in individuals with type 2 diabetes. Replication and functional validation supported a male‐specific association at the TMEM64/NECAB1 locus, highlighting the potential of sex‐informed pharmacogenomics to advance ...
Joseph H. Breeyear, John S. House, Mark Kvale, Stella Nam, Farida S. Akhtari, Hetal S. Shah, Monique M. Hedderson, Kathleen M. Giacomini, Josyf C. Mychaleckyj, Alessandro Doria, Michael J. Wagner, Josephine H. Li, Sook Wah Yee, John B. Buse, Richard P. Woychik, Daniel M. Rotroff, Alison A. Motsinger‐Reif   +16 more
wiley   +1 more source

Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac pathology and early indicators of cardiac risk

Clinical Epigenetics
Background Methylation changes linked to dilated cardiomyopathy (DCM) affect cardiac gene expression. We investigate DCM mechanisms regulated by CpG methylation using multi-omics and causal analyses in the largest cohort of left ventricular tissues ...
Konstanze Tan, Darwin Tay, Wilson Tan, Hong Kiat Ng, Eleanor Wong, Michael P. Morley, Gurpreet K. Singhera, Chang Jie Mick Lee, Pritesh R. Jain, Fei Li Tai, Paul J. Hanson, Thomas P. Cappola, Kenneth B. Margulies, Roger Foo, Marie Loh   +14 more
doaj   +1 more source

Combined gated graph convolution neural networks with multi-modal geospatial data for forest type classification

International Journal of Applied Earth Observations and Geoinformation
Forest type classification is essential for the monitoring and management of forests, with significant implications for environmental protection and the mitigation of climate change.
Huiqing Pei, Toshiaki Owari, Satoshi Tsuyuki, Takuya Hiroshima, Danfeng Hong   +4 more
doaj   +1 more source

Learning About and Learning From Sustainability Alliances: How Do SMEs Develop Dynamic Capabilities?

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how small and medium‐sized enterprises (SMEs) develop sustainability capabilities by engaging in sustainability alliances. By combining perspectives on organisational learning theory and the dynamic capabilities framework, the research investigates how SMEs develop both networking and sustainability capabilities across ...
Raffaele Silvestri, Francesca Ceruti, Elisa Carloni, Anna Romagno   +3 more
wiley   +1 more source

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

Drug Testing and Analysis, EarlyView.
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki, Anastasios Trakakis, Athanasios Theocharis, Chara Parpala, Chara Kotsailidou, Alexandros Psarianos, Emmanouil Chatzichristofis, Eleni Zagelidu, Panagiota Roussou, Nikolaos Raikos, Orthodoxia Mastrogianni   +10 more
wiley   +1 more source

Explainable hybrid stacking ensemble method for hard rock pillar stability prediction and engineering applications

Deep Underground Science and Engineering, EarlyView.
This research proposes an interpretable hybrid stacking ensemble framework, optimized by the Sparrow Search Algorithm, to enhance hard rock pillar stability prediction. By integrating six machine learning models—k‐nearest neighbors, support vector machines, random forests, Gradient Boosting Decision Tree, eXtreme Gradient Boosting, and Light Gradient ...
Ning Wang, Guoyan Zhao, Meng Wang, Taraka Pattela   +3 more
wiley   +1 more source

Evaluation of the sentinel yellow fever surveillance system in Uganda, 2017–2022: strengths and weaknesses

BMC Infectious Diseases
Background Uganda has a sentinel surveillance system in seven high-risk sites to monitor yellow fever (YF) patterns and detect outbreaks. We evaluated the performance of this system from 2017 to 2022.
Mercy Wendy Wanyana, Patrick King, Richard Migisha, Benon Kwesiga, Paul Edward Okello, Daniel Kadobera, Lilian Bulage, Joshua Kayiwa, Annet Martha Nankya, Alex Riolexus Ario, Julie R. Harris   +10 more
doaj   +1 more source