Results 141 to 150 of about 5,272,529 (322)

Validation of Remotely Sensed and Modeled Soil Moisture at Forested and Unforested NEON Sites

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Soil moisture (SM) is an important driver for forest ecosystems, creating a need for globally extensive SM information that can only be achieved with satellite-based sensors and/or process-based model.
Edward Ayres   +4 more
doaj   +1 more source

On-going transmission of human onchocerciasis in the Massangam health district in the West Region of Cameroon: Better understanding transmission dynamics to inform changes in programmatic interventions.

open access: yesPLoS Neglected Tropical Diseases, 2018
BackgroundMassangam health district (HD), in the West Region of Cameroon, has received ivermectin mass drug administration (MDA) for 20 years, however there is evidence of continued high transmission of Onchocerca volvulus.
Didier Bakajika   +8 more
doaj   +1 more source

Evaluation of TsHARP Utility for Thermal Sharpening of Sentinel-3 Satellite Images Using Sentinel-2 Visual Imagery

open access: yesRemote Sensing, 2019
A spatially distributed land surface temperature is important for many studies. The recent launch of the Sentinel satellite programs paves the way for an abundance of opportunities for both large area and long-term investigations.
Hanna Huryna   +5 more
doaj   +1 more source

Predicting severe maternal outcomes in a network of sentinel sites in Latin-American countries. [PDF]

open access: yesInt J Gynaecol Obstet, 2023
Aleman A   +8 more
europepmc   +1 more source

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

open access: yes, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B.   +7 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh   +5 more
wiley   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier   +3 more
wiley   +1 more source

New Approach for Temporal Stability Evaluation of Pseudo-Invariant Calibration Sites (PICS) [PDF]

open access: yes
Pseudo-Invariant Calibration Sites (PICS) are one of the most popular methods for in-flight vicarious radiometric calibration of Earth remote sensing satellites.
Angal, Amit   +4 more
core   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

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