Results 161 to 170 of about 5,272,529 (322)

Evaluation of the sentinel yellow fever surveillance system in Uganda, 2017–2022: strengths and weaknesses

BMC Infectious Diseases
Background Uganda has a sentinel surveillance system in seven high-risk sites to monitor yellow fever (YF) patterns and detect outbreaks. We evaluated the performance of this system from 2017 to 2022.
Mercy Wendy Wanyana, Patrick King, Richard Migisha, Benon Kwesiga, Paul Edward Okello, Daniel Kadobera, Lilian Bulage, Joshua Kayiwa, Annet Martha Nankya, Alex Riolexus Ario, Julie R. Harris   +10 more
doaj   +1 more source

Change detection in SAR time-series based on the coefficient of variation

, 2019
This paper discusses change detection in SAR time-series. Firstly, several statistical properties of the coefficient of variation highlight its pertinence for change detection. Then several criteria are proposed. The coefficient of variation is suggested
Koeniguer, Elise Colin, Nicolas, Jean-Marie   +1 more
core  

Infectious intestinal disease : do we know it all? [PDF]

, 2006
Infectious intestinal disease (IID), with associated high morbidity and considerable mortality worldwide, causes a wide spectrum of illness. This ranges from mild discomfort to illness with severe complications.
Gauci, Charmaine, Gilles, Herbert M., Mamo, Julian, O’Brien, Sarah J.   +3 more
core  

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Learning About and Learning From Sustainability Alliances: How Do SMEs Develop Dynamic Capabilities?

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how small and medium‐sized enterprises (SMEs) develop sustainability capabilities by engaging in sustainability alliances. By combining perspectives on organisational learning theory and the dynamic capabilities framework, the research investigates how SMEs develop both networking and sustainability capabilities across ...
Raffaele Silvestri, Francesca Ceruti, Elisa Carloni, Anna Romagno   +3 more
wiley   +1 more source

Fundamentals of Earth Observation Policy: Examples for German and European Missions [PDF]

, 2010
Several European countries have developed their national high resolution earth observation systems. Some of them are operated in close cooperation with industrial partners, others are dual-use missions earmarked to fulfil the needs of national security ...
Sandau, Rainer, Schmidt-Tedd, Bernhard, Schreier, Gunter   +2 more
core  

The Squalene Oil‐in‐Water Nanoemulsion Vaccine Carrier AddaVax Potentiates TLR‐Induced B‐Cell Responses

Cytometry Part A, EarlyView.
ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone, Jiin Felgner, Jenny Hernandez‐Davies, D. Huw Davies   +3 more
wiley   +1 more source

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

Fibroblast Plasticity in Inflammation of the Barrier

Barrier Immunity, EarlyView.
Under inflammatory condition, fibroblasts in barrier tissues integrate inflammatory, senescent, and mechanical inputs. These pathways activate central signaling networks to drive fibroblast phenotypic transition, enabling cytokine production, immune cell recruitment, and extracellular matrix remodeling.
Chen Zhang, Hao Wu, Wei Li
wiley   +1 more source

Performance of Sentinel-2 NDVI for assessing the relationship between vegetation and soil moisture under extreme drought conditions [PDF]

, 2012
Initial indications are that the enhanced spatial and spectral resolution of Sentinel-2 would allow for better assess- ment of vegetation condition, and consequently improved application in conditions of moisture deficit/drought.
West, H., Quinn, N., Horswell, M., White, P.   +3 more
core