Results 121 to 130 of about 34,769 (245)

Indicators to identify cancer screening providers with suboptimal case detection: A scoping review

International Journal of Cancer, Volume 158, Issue 9, Page 2339-2358, 1 May 2026.
What's new? Quality control of cancer screening programs is essential to maintaining high public health standards. Here, the authors reviewed monitoring of case detection in cervical and colorectal cancer screening programs in Europe, and evaluated its effectiveness. They analysed 20 different measures used for this purpose and showed that many of them
Jiayao Lei, Milena Falcaro, Adam R. Brentnall, James F. O'Mahony, Sisse Helle Njor, Matejka Rebolj   +5 more
wiley   +1 more source

Health of Wild Atlantic Salmon (Salmo salar) Smolts Along Coastal Migratory Routes in Newfoundland, Canada With and Without Salmonid Aquaculture as Assessed Using Sentinel Cages

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
ABSTRACT Declines in wild Atlantic salmon populations in the North Atlantic with migratory routes adjacent to commercial salmonid aquaculture operations in coastal marine environments have raised concerns about the potential for direct or indirect effects this industry may have on local wild populations.
Mark Young, Travis E. Van Leeuwen, Kimberly Marshall, Steven Duffy, Matthew Grandy, Jesse Bisson, Terry Bungay, Shannon Cross, Art Walsh, Donald Keefe, Ross Hinks, J. Brian Dempson, Mark D. Fast, Ian A. Fleming, Harry M. Murray   +14 more
wiley   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Pandemic preparedness: The case for sentinel surveillance of doctors' burnout. [PDF]

J Coll Med S Afr
Makhunga-Stevenson N.
europepmc   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Leveraging the influenza sentinel surveillance platform for SARS-CoV-2 monitoring in Bangladesh (2020-2024): a prospective sentinel surveillance study. [PDF]

Lancet Reg Health Southeast Asia
Islam MA, Hassan MZ, Akhtar Z, Bhuiya S, Shuvo TA, Ghosh PK, Asadullah, Al Jubayer Biswas MA, Rahman M, Jubair M, Begum MN, Karim Y, Rahman MZ, Hossain ME, Morshed Khan MN, Shirin T, Rubaid Anwar SNM, Alam AN, Rahman Sarker MF, Monalisa, Khan Jony MH, Rahman M, Rahman M, Aleem MA, Chowdhury F.   +24 more
europepmc   +1 more source

Predicting Risk of Lymph Node Metastasis in Neuroendocrine Carcinoma of Cervix: A Validated Nomogram Incorporating Neuroendocrine Markers and Clinical Parameters

Cancer Medicine, Volume 15, Issue 3, March 2026.
This study creates a nomogram model to predict risk probability of lymph node metastasis in NECC based on neuroendocrine biomarkers (CD56) and clinical factors. This model is superior to other existing models through the comparison. And it enables clinicians to identify low‐risk patients (risk probability threshold: 0.20) to guide the individualized ...
Mingzhu Jia, Siyuan Zeng, Juan Zou, Huiling Chen, Changsheng Lin, Shuqi Yang, Jiangchuan Pi, Xue Xiao   +7 more
wiley   +1 more source