Results 121 to 130 of about 716,209 (310)

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 42

, 2001
During week 42 (ending 21 October 2001), sentinel general practices reported 4 cases of influenza-like illness (ILI). This corresponds to a GP consultation rate of 10 per 100,000 population.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Novel surveillance design exploiting network analysis for efficient, rapid detection of emerging Clostridioides difficile strains

Nature Communications
Whole genome sequencing is being introduced in England to support national surveillance of key hospital-acquired pathogens, starting with Clostridioides difficile, to facilitate novel strain identification and enable timely interventions.
Diane Pople, Tjibbe Donker, Olisaeloka Nsonwu, Dakshika Jeyaratnam, Dimple Chudasama, Russell Hope, Susan Hopkins, Mark H. Wilcox, David W. Eyre, A. Sarah Walker, Julie V. Robotham   +10 more
doaj   +1 more source

Almanac and reference book / The Milwaukee Sentinel.

Mode of access ...
Milwaukee Sentinel.
core  

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva, Vagner Gonçalves‐Junior, Mauricio Candido da Silva, André Rinaldi Fukushima, Rose Lilian Gasparini‐Morato, Helenice de Souza Spinosa, Ana Carolina Ewbank, Carlos Sacristán, Ana de la Torre, José Luiz Catão‐Dias, Pedro Enrique Navas‐Suárez   +10 more
wiley   +1 more source

Overview: Surveillance and sentinel systems [PDF]

Journal of Urban Health, 1998
openaire   +2 more sources

Weekly Influenza Surveillance Report Week 50 2002

, 2002
The sentinel GP consultation rate for influenza-like illness has increased slightly but remains at low levels. Influenza virus has not been detected this season in sentinel or non-sentinel specimens.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Risk factors for dental overgrowth in rabbits: A retrospective study using electronic health records

Veterinary Record, EarlyView.
Abstract Background Rabbits’ teeth grow continuously. Overgrown teeth are a frequent cause for veterinary consultation and can have severe welfare implications. The risk factors for overgrown teeth are incompletely understood. Methods Rabbits with overgrown teeth recorded in their electronic health records (EHRs) were identified from a large population
Mary A. Coles, Alan D. Radford, Melanie Chapman   +2 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source