Results 261 to 270 of about 156,386 (347)

CIPHER: An end-to-end framework for designing optimized aggregated spatial transcriptomics experiments. [PDF]

open access: yesPLoS Comput Biol
Hemminger Z   +5 more
europepmc   +1 more source

Macrocyclization of ω‐Isocyano Aldehydes

open access: yesAngewandte Chemie, EarlyView.
The ω‐isocyano aldehydes readily undergo cyclization to afford α‐acyloxy, α‐hydroxy, α‐acetamido, and α‐keto macrolactams, as well as tetrazole‐fused macrocycles, via C(sp3)─C(sp2) bond formation, providing access to diverse α‐functionalized medium‐sized lactams and macrolactams. ABSTRACT Medium‐sized rings and macrocycles constitute a privileged class
Baochao Yang   +4 more
wiley   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

open access: yesAngewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani   +7 more
wiley   +1 more source

From cradle to Tic: early developmental profiles of tourette syndrome and its comorbidities in the MoBa cohort. [PDF]

open access: yesEur Child Adolesc Psychiatry
Emmanuel S   +9 more
europepmc   +1 more source

Structured multi-domain EEG descriptors with phase-based connectivity for lie and truth detection. [PDF]

open access: yesMethodsX
Surya DU   +5 more
europepmc   +1 more source

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