Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith +6 more
wiley +1 more source
The Adult Separation Anxiety Questionnaire (ASA-27): reliability of the German translation, factor structure, and concurrent validity with anxiety sensitivity and agoraphobic cognition. [PDF]
Seuling PD +11 more
europepmc +1 more source
Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim +6 more
wiley +1 more source
Development of a Computerized Adaptive Test for Separation Anxiety Disorder Among Adolescents. [PDF]
Hu Y, Cai Y, Tu D, Guo Y, Liu S.
europepmc +1 more source
Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova +27 more
wiley +1 more source
Separation Anxiety Symptom Profiles and Parental Accommodation Across Pediatric Anxiety Disorders. [PDF]
Phillips KE, Norris LA, Kendall PC.
europepmc +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Psychological strains after the crisis: evaluating separation anxiety among Iranian children and adolescents in the post-COVID-19 era. [PDF]
Vossoughi M +8 more
europepmc +1 more source
Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht +3 more
wiley +1 more source
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source

