Results 81 to 90 of about 1,659,581 (265)

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Effect of Theraplay-Based Play Therapy on Separation Anxiety in Elementary School Girls: A Randomized Controlled Trial [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: School-age children often experience separation anxiety due to being away from their families. A therapeutic approach to address this issue is Theraplay-based play therapy.
Rozita Kaviani, Nafiseh Hekmatipur
doaj  

Anxiety in childhood [PDF]

, 2003
Anxiety is an everyday term, but what do we mean by it? Anxiety involves a sense of apprehension, with accompanying physiological reactions, typically associated with worrying about the future.   How does anxiety present itself in children?
Margie Richardson
core  

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

The missing link between late-onset separation anxiety and dementia

Journal of Geriatric Mental Health, 2018
Relation of behavioral and psychological symptoms with dementia has several implications. They predict treatment and prognosis in patients. Anxiety and its association as a psychological symptom despite being well known is not addressed properly in ...
Lokesh Kumar Singh, Spoorthy Sai Mamidipalli, Narendra K Bodhey, Neethu K Nandan, Nobal Chandrakar   +4 more
doaj   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Designing and evaluating the efficacy of interactive drawing methods based on parent-child relationship on the symptoms of separation anxiety disorder in 6-8 year old children [PDF]

مجله علوم روانشناختی
Background: Separation anxiety disorder is one of the most common psychological disorders in childhood. Parenting styles and parental anxiety are among the important risk factors that have been identified for the occurrence of separation anxiety disorder.
Nooshin Torabi Goodarzi, Afsaneh Nazeri, Amir Ghamarani   +2 more
doaj  

ANXIETY DISORDERS AND DEPRESSION IN CHILDREN WITH FUNCTIONAL SOMATIC SYMPTOMS- A CASE-CONTROL STUDY FROM INDIA

The Indonesian Journal of Public Health
Introduction: Nearly 10% of children and adolescents suffer from functional somatic symptoms (FSS) which are persistent, bothersome bodily symptoms not having demonstrable organic pathology. Associations have been reported between children’s FSS, anxiety,
Sreedevi P A, Suma Balan, Gitanjali Natarajan, Bhanu Vikraman Pillai, C Jayakumar, Sheejamol V. S   +5 more
doaj   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source