Optimal model‐based design of experiments for parameter precision: Supercritical extraction case
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley +1 more source
A systematic review of methylome-wide associations with anxiety disorders. [PDF]
Ingram SJ +6 more
europepmc +1 more source
Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co‐administration with CYP3A4‐inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the clinical impact of these interactions is unknown.
Tony Antoniou +7 more
wiley +1 more source
Pediatric-Onset and Adult-Onset Separation Anxiety Disorder Across Countries in the World Mental Health Survey. [PDF]
Silove D +21 more
europepmc +1 more source
Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review
Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović +4 more
wiley +1 more source
A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel +3 more
wiley +1 more source
The impact of a pandemic as an example of a stressful event, on anxiety and related emotional disorders of NF1 patients compared to healthy children. [PDF]
Cohen R, Aharoni S, Halevy A, Genizi J.
europepmc +1 more source
Resilience Practices and Post‐Traumatic Growth Among Sudanese IDPs
ABSTRACT In this paper we examine the resilience of internally displaced persons (IDPs) in Sudan who have endured various forms of suffering resulting from being targeted or trapped by militants involved in large‐scale violence. Upon escaping the conflict zones, the civilians exhibit strength, adaptability, and wisdom in the face of various threats to ...
Karina Korostelina +2 more
wiley +1 more source
Conceptualizing Autism as a Behavioral Network: Transdiagnostic Associations with Co-occurring Psychiatric Conditions. [PDF]
Han GT +14 more
europepmc +1 more source
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota +8 more
wiley +1 more source

