Results 131 to 140 of about 9,236,417 (302)

An exposome atlas of serum reveals the risk of chronic diseases in the Chinese population

Nature Communications
Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we collected serum samples from 5696 healthy people
Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu   +16 more
doaj   +1 more source

Copper phosphide coupled with amorphous ruthenium on scaffold surfaces synergistically enhances hydrogen production

Nano Research
Water electrolysis is an ideal way to obtain “green hydrogen”, but the core challenge of its commercial application is to develop advanced electrocatalysts that can work efficiently and stably under wide pH conditions.
Miaoyang Yu, Qiao Ye, Linfeng Xiao, Xiaojun Zeng, Feng Wang, Abdukader Abdukayum, Chuan Zuo, Weiping Liu, Nianpeng Li, Guangzhi Hu, Xue Zhao   +10 more
doaj   +1 more source

Demonstration of Separation Control Using Dielectric Barrier Discharge Plasma Actuators. [PDF]

AIAA J, 2018
Hultgren LS, Ashpis DE.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Separation control of a NACA 4412 with 25° sweep at high Reynolds numbers using pulsed-jet actuators

International audienceBoundary-layer separation at large Reynolds numbers over swept wings remains a challenging phenomenon to either replicate in well-controlled laboratory experiments or predict in full-scale applications.
Loyer, Stéphane, Kourta, Azeddine, Baldas, Lucien, Orieux, Stéphane, Quesada, Guillermo Lopez, Mazellier, Nicolas, Leelaburanathanakul, Phassawat, Batikh, Ahmad, Passaggia, Pierre-Yves, Barrot-Lattes, Christine   +9 more
core   +1 more source

Effects of Sweeping Jet Actuator Parameters on Flow Separation Control. [PDF]

AIAA J, 2018
Koklu M.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Plasma Streamwise Vortex Generators for Flow Separation Control on Trucks: A Proof-of-concept Experiment. [PDF]

Flow Turbul Combust, 2018
Vernet JA, Örlü R, Söderblom D, Elofsson P, Alfredsson PH.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Adaptive Separation Control System Using Vortex Generator Jets for Time-Varying Flow

Journal of Applied Fluid Mechanics, 2008
Flow separation is mostly an undesirable phenomenon and boundary layer control is an important technique for flow separation problems on airfoils and in diffusers.
H Hasegawa, S Kumagai
doaj