Results 121 to 130 of about 573,828 (318)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
An Airspace Simulator for Separation Management Research [PDF]
, 2011 Air Traffic Management (ATM) systems are undergoing a period of major transformation and modernisation, requiring and enabling new separation management (SM) methods.
Flathers, George W.
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Influences of Two-Phase Outlet on Axial Vortex Separator
Shiyou jixieInvestigating the internal flow field distribution of the axial vortex separator and the influences of structural parameters on the internal flow field is necessary to effectively predict the performance of the separator and design a more efficient ...
Lou Huanwei +5 more
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Numerical Simulation on Flow Field Characteristics of Centrifugal Supergravity Oil/Water Separator
Shiyou jixieAs oilfield exploitation gradually enters high water cut stage,the performance requirements for oil/water separator are becoming increasingly stringent.However,the existing oil/water separators fall behind such requirements,and further efforts are ...
Luan Zhiyong +6 more
doaj
The preparation and characterisation of hydrophobic polymeric membranes for use in the separation of liquid mixtures using pervaporation separation processes [PDF]
, 1998 Pervaporation is a membrane separation process used to separate liquid mixtures Separation is achieved by establishing a concentration vapour-pressure gradient across the membrane.
Byrne, Susan M.
core