Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Probabilistic quality assurance of biopsy DVH thresholds in HDR prostate brachytherapy under localization uncertainty. [PDF]
Muscat M +4 more
europepmc +1 more source
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Caveats on Using Firth's Penalization in the Model-Based Regression Standardization for Rare Diseases. [PDF]
Hashibe S, Hongo W, Shinozaki T.
europepmc +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Classifying OECD Health Systems by Financing Structure: An Empirical Latent Profile Analysis. [PDF]
Aydın JC, Yaşar G.
europepmc +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Evolutionary Imprints on the Foliar Elementome: Biogeochemical Niche Differentiation Among <i>Fagus</i> Species. [PDF]
Cárate Tandalla D +7 more
europepmc +1 more source
Coparenting Closeness and Psychological Distress as Predictors of Life Satisfaction Among Romanian Divorced and Separated Parents. [PDF]
Apostol MM +3 more
europepmc +1 more source
Machine learning-driven estimation of microplastic percentage yield for rapid and accurate quantification. [PDF]
Kang YG, Choi J, Lee JY, Oh TK, Sung J.
europepmc +1 more source

