Results 51 to 60 of about 194,436 (277)

Evaluation of outcomes of 5cm all-around mesh reinforcement after endoscopic component separation and midline closure during laparoscopic ventral hernia repair

, 2021
Background: To evaluate the short term recurrence, pain scores, infection rates and cost factors by using 5cm all around composite mesh reinforcement of the closed defect after endoscopic video-assisted component separation for large ventral hernia ...
Samal, Satyajit, Sharma, Deborshi, Shrivastava, Nishit, Lal, Romesh, Kumar Gupta, Ravi   +4 more
core   +1 more source

Emergency separation of conjoined twins in a tertiary hospital in Indonesia: three case reports

BMC Medical Ethics, 2023
Background Emergency separation of conjoined twins is performed when one twin is already dead or dying and threatens the survival of the other. The particular decision to perform an emergency separation of conjoined twins provides an ethical dilemma that
Andi Ade Wijaya Ramlan, Raihanita Zahra, Kshetra Rinaldhy, Christopher Kapuangan, Rahendra, Komang Ayu Ferdiana, Ahmad Yani   +6 more
doaj   +1 more source

Identification and Characterization of Robust Hepatocellular Carcinoma Prognostic Subtypes Based on an Integrative Metabolite‐Protein Interaction Network

Advanced Science, 2021
Metabolite‐protein interactions (MPIs) play key roles in cancer metabolism. However, our current knowledge about MPIs in cancers remains limited due to the complexity of cancer cells. Herein, the authors construct an integrative MPI network and propose a
Di Chen, Yiran Zhang, Wen Wang, Huan Chen, Ting Ling, Renyu Yang, Yawei Wang, Chao Duan, Yu Liu, Xin Guo, Lei Fang, Wuguang Liu, Xiumei Liu, Jing Liu, Wuxiyar Otkur, Huan Qi, Xiaolong Liu, Tian Xia, Hong‐Xu Liu, Hai‐long Piao   +19 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Primary Epithelioid Hemangioendothelioma of the Spine: A First in Africa. A Case Report and Literature Review

Clinical Case Reports
Primary Epithelioid hemangioendothelioma of the spine is an ultra‐rare malignant vascular neoplasm with no pathognomonic clinical features and as such requires a high index of suspicion and a multi‐disciplinary and multimodality treatment approach.
Bakang Abiot Kgaodi, Jed Saul Lazarus, Brendon Price, Stefan Kruger, Crispin Thompson   +4 more
doaj   +1 more source

HDNA methylation data-based molecular subtype classification related to the prognosis of patients with hepatocellular carcinoma

BMC Medical Genomics, 2020
Background DNA methylation is a common chemical modification of DNA in the carcinogenesis of hepatocellular carcinoma (HCC). Methods In this bioinformatics analysis, 348 liver cancer samples were collected from the Cancer Genome Atlas (TCGA) database to ...
Hui He, Di Chen, Shimeng Cui, Gang Wu, Hailong Piao, Xun Wang, Peng Ye, Shi Jin   +7 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Aggressive Surveillance Is Needed to Detect Endoleaks and Junctional Separation between Device Components after Zenith Fenestrated Aortic Reconstruction

, 2019
Background Junctional separation and resulting type IIIa endoleak is a well-known problem after EVAR (endovascular aneurysm repair). This complication results in sac pressurization, enlargement, and eventual rupture.
Wang, S. Keisin, Dalsing, Michael C., Gupta, Alok K., Sawchuk, Alan P., Motaganahalli, Raghu L., Fajardo, Andres, Lemmon, Gary W., Murphy, Michael P.   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Particle separation using ultrasound can radically reduce embolic load to brain after cardiac surgery. [Elektronisk resurs]

, 2004
Background. Microembolism during cardiopulmonary bypass has been suggested as being the predominant cause of neurocognitive disorders after cardiac surgery.
Bjursten, Henrik,, Lenshof, Andreas,, Pettersson, Filip, Holm, Cecilia,, Lund University., Johansson, Per, Laurell, Thomas,   +6 more
core   +1 more source