Results 91 to 100 of about 196,958 (305)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Nmerical Simulation of Horizontal Separator for Sand Laden Heavy Oil

Shiyou jixie, 2022
At present, the Nmerical studies on the separator are extensive, but most of them focus on the simulation of the flow field under different components, and there is a lack of analysis on the influence of the deposition rate of particles in the horizontal
Jing Jiaqiang, Cheng Yuanzhao, Zhang Shijian, Shan Yuting, Li Denghui, Yang Hang, Shi Yunliang   +6 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Structure and properties of POSS-(PMMA₄₆)₈ impregnated commercial polypropylene separator

Cailiao gongcheng, 2019
In order to improve the safety and reduce interface impedance of lithium-ion batteries, the star-shaped polyhedral POSS-poly(methyl methacrylate) (POSS-(PMMA46)8), which has both excellent heat resistance and good compatibility with the polymer material,
MA Jing-yu, YANG Kai-qi, ZHANG Min, YANG Han, MA Xiao-yan   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Spacecraft nitrogen generation [PDF]

Two spacecraft nitrogen (N2) generation systems based on the catalytic dissociation of hydrazine (N2H4) were evaluated. In the first system, liquid N2H4 is catalytically dissociated to yield an N2 and hydrogen (H2) gas mixture.
Carlson, J. N., Kacholia, K. K., Marshall, R. D., Powell, J. D.   +3 more
core   +1 more source

Upaya Peningkatan Produksi Gas Pada Separator Terpasang Di Stasiun Pengumpul Gas Musi Barat PT. Pertamina Ep Asset 2 Pendopo Field [PDF]

, 2014
Berdasarkan pengamatan lapangan, separator terpasang mempunyai variabel terpasang yaitu luas bagian dalamseparator (Ag) sebesar 13,7 ft² dan dimensi separator (IDxH) adalah 5,91 ft x 14,76 ft dengan target produksi 45,17MMSCFD.
amin, M. (muhammad), herlina, W. (weny), hidayat, R. (rahmat)   +2 more
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Separation logic [PDF]

Communications of the ACM, 2019
Separation logic is a key development in formal reasoning about programs, opening up new lines of attack on longstanding problems.
openaire   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source