Results 201 to 210 of about 875,517 (356)

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis   +9 more
wiley   +1 more source

INTEGRATED PRE-HOSPITAL AND HOSPITAL BASED DIGITAL, LABORATORY, AND HOST RESPONSE DIAGNOSTICS FOR EARLY SEPSIS DETECTION AND TIMELY ANTIMICROBIAL OPTIMIZATION: A SYSTEMATIC REVIEW

open access: green
IBRAHIM MUHAMMAD AL-AREJ   +7 more
openalex   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi   +12 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Machine Learning Model for Sepsis Prediction in Prolonged and Chronic Critical Illness: Development and Validation Using Retrospective Real-World ICU Data. [PDF]

open access: yesJ Clin Med
Yadgarov MY   +7 more
europepmc   +1 more source

Prevalence of sepsis, malaria, malnutrition, and pneumonia in the causal chain of death among minimally invasive tissue sampling (MITS)-eligible decedents aged 28 days to 59 months enrolled in the Kenya Child Health and Mortality Prevention Surveillance (CHAMPS) sites from February 1, 2018, to March 31, 2022.

open access: green
Susan Gachau (5233919)   +15 more
openalex   +1 more source

LPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis [PDF]

open access: bronze, 2019
Giuseppe Stefano Netti   +17 more
openalex   +1 more source

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