Results 201 to 210 of about 875,517 (356)
A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis
Arthritis &Rheumatology, Accepted Article.Objective
Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker +9 morewiley +1 more sourceEfficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study
Arthritis &Rheumatology, Accepted Article.Objective
The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods
Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, The TULIP‐SC investigators +12 morewiley +1 more sourceAASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro +6 morewiley +1 more sourcePrevalence of sepsis, malaria, malnutrition, and pneumonia in the causal chain of death among minimally invasive tissue sampling (MITS)-eligible decedents aged 28 days to 59 months enrolled in the Kenya Child Health and Mortality Prevention Surveillance (CHAMPS) sites from February 1, 2018, to March 31, 2022.
Susan Gachau (5233919), Victor Akelo (450373), Angela Cleveland (21262783), Joyce Were (21262786), Sammy Khagayi (382839), Daniel Kwaro (546059), Miriam Taegtmeyer (338775), David Obor (4723632), Aggrey Igunza (21262789), Stephen Munga (293621), Richard Omore (2636782), Thomas Misore (13267607), George Aol (310311), Dickens Onyango (8195922), Beth A. Tippett Barr (5368208), Rachael Joseph (11141501) +15 moreopenalex +1 more sourceLPS removal reduces CD80-mediated albuminuria in critically ill patients with Gram-negative sepsis [PDF]
, 2019 Giuseppe Stefano Netti, Fabio Sangregorio, Federica Spadaccino, Francesco Staffieri, Antonio Crovace, Barbara Infante, Annamaria Maiorano, Giulia Godeas, Giuseppe Castellano, Anna Maria Di Palma, Clelia Prattichizzo, Antonella Cotoia, Lucia Mirabella, Loreto Gesualdo, Gilda Cinnella, Giovanni Stallone, Elena Ranieri, Giuseppe Grandaliano +17 moreopenalex +1 more source