Results 201 to 210 of about 536,044 (309)

Aligning neonatal sepsis triage diagnostics with WHO target product profiles in low- and middle-income countries. [PDF]

BMJ Glob Health
Gleeson B, Blumel B, Ibarz Pavon AB, Kirby RP, Hansen C, Erkosar B, Spotswood NE, Nisar YB, Palamountain KM.   +8 more
europepmc   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Severe Sepsis After Vaginal Delivery: A Case Report. [PDF]

Case Rep Obstet Gynecol
Dehghan M.
europepmc   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

A machine learning system enables just-in-time risk-stratified sepsis evaluations in the neonatal intensive care unit. [PDF]

J Perinatol
Kumar NK, Phillips A, Gootenberg DB, Vesoulis ZA, Viehl LT.   +4 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Microbial proteases and endothelial barrier disruption in sepsis: A neglected nexus. [PDF]

Virulence
Rao SS, Shenoy M S, Gutti RK, Prabhu V, Joshi M, Nayak UY, Bharath Prasad AS.   +6 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Source-controlled bacterial peritonitis improves survival but leaves persistent lung inflammation and airway IgA loss. [PDF]

Intensive Care Med Exp
Kato A, Saito M, Miyazaki H, Kearney BM, Nakashima M, Nakashima H, Koyama K, Kinoshita M.   +7 more
europepmc   +1 more source

Liver sepsis

Journal of British Surgery, 1964
N A, MATHESON, D L, GARDNER, H A, DUDLEY
openaire   +2 more sources