Results 201 to 210 of about 895,147 (354)

Multi-Omics Reveals Dysregulation of the Endosome-Lysosome-Autophagy Axis and Immune-Inflammatory Imbalance in Elderly Sepsis. [PDF]

Clin Interv Aging
Gou Y, Xia Z, Haireti N, Aikepaer A, Yang J, Li D.   +5 more
europepmc   +1 more source

Characteristics of early-onset neonatal sepsis caused by Escherichia coli

, 2012
Chin-Han Tsai, Yi‐Yung Chen, Kuo‐Gon Wang, Chen‐Yu Chen, Chie-Pein Chen   +4 more
openalex   +1 more source

Supratherapeutic drug concentration triggers: A novel data‐driven approach to assess their value for medication safety surveillance in intensive care

British Journal of Clinical Pharmacology, EarlyView.
Aims Electronic triggers (e‐triggers) are used as screening signals to detect potential adverse drug events (ADEs) and offer an effective system level approach for medication safety surveillance. Their clinical utility is typically evaluated through time‐consuming manual chart review by experts, limiting implementation.
Anne Paulien Langermans, Izak A. R. Yasrebi‐de Kom, Dylan Wayne de Lange, Nicolette Fransisca de Keizer, Joanna E. Klopotowska, on behalf of the RESCUE Study group, C. S. C. Bouman, E. N. van Roon, P. F. Schutte, J. ten Cate, D. van Balen, S. Hendriks, C. Lau, W. J. Vermeijden, A. Beishuizen, J. B. Masselink, P. E. Spronk, H. J. M. van Kan, P. W. de Feiter, E. J. Wils, A. Wieringa, A. J. Valkenburg, W. M. van den Bergh, M. H. Renes, W. Bult, E. de Jonge, M. Hoeksema, E. J. Wesselink, I. M. Purmer, B. E. Bosma, S. H. W. van Bree, H. J. W. Lammers, R. J. Bosman, E. J. F. Franssen, A. Karakus, M. Sigtermans, E. M. Kuck, D. A. Dongelmans, M. J. H. Aries, E. V. Uijtendaal, M. C. Reuland   +40 more
wiley   +1 more source

The new SOFA for sepsis identification and mortality prediction: a multicenter cohort study. [PDF]

J Intensive Care
Zhao L, Cui Q, Liu J, Dong S, Zong L, Yang F, Shi H, Wang Y, Zhao X, Li H, Fang Y, Gao Y, Pei H, Su F, Zhang H, De Backer D, Li Y, Xie K.   +17 more
europepmc   +1 more source

A probiotic strain of Escherichia coli, Nissle 1917, given orally exerts local and systemic anti‐inflammatory effects in lipopolysaccharide‐induced sepsis in mice [PDF]

, 2009
Belén Arribas, Maria Elena Rodríguez‐Cabezas, Desirée Camuesco, Mónica Comalada, Elvira Bailón, P. Utrilla, Ana Nieto, Ángel Concha, Antonio Zarzuelo, Júlio Gálvez   +9 more
openalex   +1 more source

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Which Bacterial Agent Is More Influential in the Development of Retinopathy of Prematurity: Gram-Positive or Gram-Negative? [PDF]

Children (Basel)
Yeke B, Akin MS, Butun Turk S, Elbayiyev S, Ceran B, Ozdemir O, Cakir U.   +6 more
europepmc   +1 more source

Prophylactic Antioxidant Potential of Gallic Acid in Murine Model of Sepsis [PDF]

, 2014
Harikesh Maurya, Vaishali Mangal, Sanjay Gandhi, K Prabhu, K Ponnudurai   +4 more
openalex   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Influence of Sepsis on Clinical Outcomes During Mechanical Circulatory Support by Microaxial Flow Pump in Patients with Cardiogenic Shock Following Acute Myocardial Infarction. [PDF]

J Clin Med
Düsing P, Markgraf J, Al-Kassou B, Bulic M, Beiert T, Zimmer S, Werner N, Jansen F, Nickenig G, Zietzer A.   +9 more
europepmc   +1 more source