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Sepsis and Thrombosis

Seminars in Thrombosis and Hemostasis, 2013
Activation of coagulation frequently occurs in severe infection and sepsis and may contribute to the development of thrombosis. Coagulation abnormalities in sepsis range from a small decrease in platelet count and subclinical prolongation of global clotting times to fulminant disseminated intravascular coagulation (DIC), characterized by simultaneous ...
Levi, Marcel   +2 more
openaire   +2 more sources

Sepsis

The Lancet
Sepsis is defined as a dysregulated host response to infection that leads to life-threatening organ dysfunction. The infectious insult triggers a dysregulated immune response that variably activates and suppresses multiple body system functions. Susceptibility to either developing or succumbing to sepsis is influenced by pathogen load and virulence ...
Mervyn, Singer   +11 more
openaire   +2 more sources

Plasmapheresis in Sepsis

2001
Despite the impressive advances in our understanding of the basic mechanism of sepsis, mortality associated with sepsis remains high. Some experimental and clinical evidence suggests that hemofiltration or other technics commonly used in the continuous renal replacement therapies are able to remove sepsis mediators, although the precise mechanism ...
BERLOT, GIORGIO   +3 more
openaire   +4 more sources

Oxidative metabolism in sepsis and sepsis syndrome

Journal of Critical Care, 1995
The high mortality associated with sepsis syndrome and multiple organ dysfunction syndrome has persisted despite extraordinary research efforts in the laboratory and the intensive care unit. These syndromes produce systemic tissue damage that is likely to result from widespread inflammation and subsequent endothelial injury.
D E, Taylor, C A, Piantadosi
openaire   +2 more sources

Characterization of Sepsis and Sepsis-Associated Encephalopathy

Journal of Intensive Care Medicine, 2017
Background: Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its
Qing, Feng   +8 more
openaire   +2 more sources

Sepsis and cholestasis

Clinics in Liver Disease, 1999
Sepsis-associated cholestasis should always be considered as part of the differential diagnosis of jaundice in the hospitalized or critically ill patient. The development of a disproportionate elevation of serum bilirubin in comparison with serum alkaline phosphatase and serum aminotransferases should be considered an early warning sign of an ...
openaire   +3 more sources

Obesity and Sepsis

Journal of Intensive Care Medicine, 2006
Obesity has reached epidemic proportions over the last few decades. Obesity is associated with increased morbidity and mortality in hypertension, cardiovascular diseases, stroke, and cancer and is feared to decrease overall life expectancy over the next few decades.
Vidula, Vachharajani, Shantel, Vital
openaire   +2 more sources

Sepsis Biomarkers

2018
info:eu-repo/semantics ...
Vincent, Jean Louis, Lelubre, Christophe
openaire   +2 more sources

Sepsis in surgical patients: Burn sepsis

Surgery
Patients with large burn injuries remain a challenge. The loss of skin barrier integrity and induced immunosuppression after injury increases their vulnerability to infection. Sepsis remains the primary cause of death for burn-injured patients who survive their acute injury and resuscitation.
Shawn, Tejiram, Jeffrey W, Shupp
openaire   +2 more sources

Sepsis or SEPSIS

Pediatric Critical Care Medicine, 2014
Patricia, Fontela, Jacques, Lacroix
openaire   +2 more sources

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