Results 191 to 200 of about 71,686 (293)

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

British Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien, Burabha Pussadhamma, Sirimas Kanjanawart, Thikhumporn Areesinpitak, Nontaya Nakkam, Chingching Foocharoen, Wichittra Tassaneeyakul, Suda Vannaprasaht   +7 more
wiley   +1 more source

Aberrant and ectopic cell populations in restrictive allograft syndrome after lung transplantation. [PDF]

Eur Respir J
Leiber LM, Christian L, Neubert L, Ruwisch J, Yilmaz H, Schwarz EKJ, Langer LT, Kamp JC, Greer M, Haermeyer B, Kühnel M, Werlein C, Justet A, Bergmann AK, Beeckmans H, Ballmaier M, Salman J, Vos R, Knudsen L, Martin U, Vanaudenaerde BM, Yildirim AÖ, Hohlfeld JM, Ius F, Laenger F, Welte T, Falk C, Kaminski N, Jonigk DD, Gottlieb J, Schupp JC.   +30 more
europepmc   +1 more source

Functional Diversity and Oleaginous Potential of Fungal Strains From Hawaiian Soil Ecosystems

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Fungi represent an important but underexplored resource for microbial lipid production, including nutritionally valuable polyunsaturated fatty acids. Hawaiian soils, shaped by volcanic parent materials and strong environmental gradients, provide a unique setting for discovering functionally diverse fungal strains with distinct metabolic traits.
Yu Wang, Adam Phelps, Zhiqing Fang, Qian Li, Ty Shitanaka, Taren Bouwman, Luke H. Amerine, Abigail Rohy, Kyla Mei A. Tuazon, Zhiyue Wang, Samir Kumar Khanal, Nhu Nguyen, Zhi‐Yan Du   +12 more
wiley   +1 more source

Maxillary sinus morphology and septa: a cadaver-based study. [PDF]

Sci Rep
Bozhikova E, Harizanova Z, Uzunov N.
europepmc   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Differentiation of Lipedema Nodules and Angiolipomas Based on the Ultrasound and Histopathologic Findings: A Case Series. [PDF]

Cureus
Vargas D, Foureaux TO, Wortsman X, Sigrist RMS, Lellis R, Chagas LC, Saiki PY, Riedel L, Bizareli GN, Fontan C, Zattar L, Silva ACG, Dini SA, Rezende J, Prudente D, Ducati EP, Carvalho KMD, Melo DC, Cunha IW, Bernardi WH, Bezerra AS, Amato AC, Bueno AN.   +22 more
europepmc   +1 more source

The Cutaneous Branch of the Obturator Nerve: Common Finding or a Rarity Worthy of Note

Clinical Anatomy, EarlyView.
ABSTRACT According to textbook descriptions, branches of the femoral and obturator nerves provide the sensory innervation to the medial side of the thigh. However, as the exact prevalence of the obturator nerve's cutaneous branch is unknown, an anatomic study was conducted to reveal its role in providing cutaneous innervation to the medial thigh ...
Christoph Fuchssteiner, Theresia Stigger, Gerlinde M. Gruber, Peter. C. Brugger   +3 more
wiley   +1 more source

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Anatomy of the Soft Palate and Its Role in Upper Airway Function: A Narrative Review

Clinical Anatomy, EarlyView.
ABSTRACT The soft palate is a complex anatomical structure, located at the posterior aspect of the oral and nasal cavities, able to dynamically create valve closure of the nasal and the oral cavities. Its precise movement is critical for speech, swallowing, and respiration. Despite its functional importance, detailed characterization of its constituent
James C. D. Miller, Nikki Mills, Ho‐Fung Chan, Alys R. Clark, S. Ali Mirjalili   +4 more
wiley   +1 more source