Results 61 to 70 of about 71,686 (293)

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

The Septa Letters

, 2005
Cover for The Septa Letters, from the RISD Library Zine Collection.https://digitalcommons.risd.edu/specialcollections_zinecollection/1827/thumbnail ...
Collections, Special, Library, Fleet, Rywelski, Elizabeth   +2 more
core   +1 more source

Analysis of maxillary sinus septa by cone-beam computed tomography

Revista de Odontologia da UNESP, 2019
Introduction Pneumatization of the maxillary sinus may make it impossible to insert implants directly in the posterior region of the maxilla, and in these cases, the solution is to submit the patient to maxillary sinus floor augmentation surgery.
Camila Furtado de SOUZA, Adriano de Oliveira LOURES, Daniella Guedes de Figueiredo LOPES, Karina Lopes DEVITO   +3 more
doaj   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

ANALISA SISTEM BAHAN BAKAR INJEKSI PADA MESIN BENSIN MENGGUNAKAN SCAN TOOLS DAN GAS ANALYZER

Jurnal Teknik Mesin, 2017
Dalam hal perbaikan kendaraan mesin modern banyak sekali fenomena kendaraan lama dikerjakan dibengkel karena permasalahan yang cukup komplek. Terkadang permasalahan belum tentu terbaca langsung oleh scan tools sehingga diperlukan analisa lebih lanjut ...
Septa Pamungkas
doaj   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

Advanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi, Antonio Ferraro, Francesco Coccimiglio, Tiziana Ritacco, Alberto Astolfo, Michele Giocondo, Vincenzo Formoso, Raffaele Giuseppe Agostino, Francesco Iacoviello, Ioannis Papakonstantinou, Alessandro Olivo   +10 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Characteristics and prevalence of underwood's septae on digital panoramic radiographs

Journal of Indian Academy of Oral Medicine and Radiology, 2020
Background: The term Underwood's septae is eponymously used for maxillary sinus septae. Septae may be defined as cortical bony partitions found in the form of inverted gothic arches that protrude from the sinus walls, dividing the sinus into two or more ...
Anudeep Raina, M K Sunil, Lucy Pradhan, Garima Yeluri, S V Ravindra, Roopika Handa   +5 more
doaj   +1 more source

An analysis of frequency, morphology, and locations of maxillary sinus septa using cone beam computed tomography

, 2016
© 2016 by Quintessence Publishing Co Inc.To evaluate the frequency, morphology, and locations of maxillary sinus septa using cone beam computed tomographic (CBCT) imaging of the entire maxillary sinus and to analyze factors influencing the presence or ...
Seiffert, Carol, Buser, D, Buser, D., Seiffert, C, Bornstein, M.M., Seiffert, Carol Elisabeth Cori, Jacobs, Reinhilde, Bornstein, MM, von, Arx T, Seiffert, C., Fodich, I., Fodich, Ivo, Maestre-Ferrin, L, Jacobs, R., Maestre-Ferrín, L., Fodich, I, Buser, Daniel, Jacobs, R,, von Arx, T., Bornstein, Michael, von Arx, Thomas, Michael M. Bornstein, Michael, Bornstein, Michael M., Maestre-Ferrín, Laura, Buser, Daniel Albin   +24 more
core   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source