Results 111 to 120 of about 5,715 (232)

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function [PDF]

, 2012
Background-Hypertrophic cardiomyopathy (HCM), typically characterized by asymmetrical left ventricular hypertrophy, frequently is caused by mutations in sarcomeric proteins.
Alcalai R, Aref Najafi, Cris dos Remedios, Dennis Dooijes, Diederik W.D. Kuster, E. Rosalie Paalberends, Folkert J. ten Cate, Ger J.M. Stienen, Jolanda van der Velden, Lucie Carrier, Marjon van Slegtenhorst, Messer AE, Michelle Michels, Nicky M. Boontje, Sabine J. van Dijk, Sakthivel Sadayappan, Tong CW   +16 more
core   +1 more source

Early Detection of Treatment Response to Mavacamten in Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Regurgitation Using Magnetocardiography

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Recent evidence highlights the efficacy of mavacamten in reducing left ventricular outflow tract (LVOT) gradients in patients with hypertrophic cardiomyopathy (HCM), which is illustrated in this case. Additionally, the potential of magnetocardiography (MCG) as a novel, objective diagnostic and monitoring tool for nonischemic cardiomyopathies ...
Phillip Suwalski, Gamze Satilmis, Markus Reinthaler, Ulf Landmesser, Bettina Heidecker   +4 more
wiley   +1 more source

Gold Laser Cricopharyngeal Myectomy for Cricopharyngeal Dysfunction

The Laryngoscope, Volume 135, Issue 8, Page 2713-2719, August 2025.
Endoscopic treatment for cricopharyngeal bar with or without diverticulum has become the preferred option in management. However, critics cite high recurrence rates. This study evaluated a modified endoscopic approach of cricopharyngeal myectomy, removing a block of tissue with a Gold laser, to treat 84 patients with CP bar, demonstrating significantly
Jacqui Allen, Brian Yeom, Shakeela Saleem, Rebecca Hammond, Anna Miles   +4 more
wiley   +1 more source

Alcohol septal ablation for obstructive hypertrophic cardiomyopathy [PDF]

, 2015
Hypertrophic cardiomyopathy is an inhered heart disease characterised by a thickened heart muscle, common in 1:500 persons. Obstruction of blood flow in the heart due the thickened heart muscle can occur and cause dyspnoea.
Steggerda, Robbert
core   +6 more sources

Procedural Volume and Outcomes After Septal Reduction Therapies in Hypertrophic Obstructive Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Septal myectomy and alcohol septal ablation (ASA) are septal reduction therapies for patients with symptomatic obstructive hypertrophic cardiomyopathy.
Nirav Patel, Naman S. Shetty, Mokshad Gaonkar, Abdulla Shahid, Girija P. Divekar, Akhil Pampana, Nehal Vekariya, Peng Li, Mustafa I. Ahmed, Garima Arora, Pankaj Arora   +10 more
doaj   +1 more source

Prognostic Value of Coronary Angiography‐Derived Index of Microvascular Resistance in Patients With Hypertrophic Cardiomyopathy

MedComm, Volume 6, Issue 8, August 2025.
With an angio‐IMR threshold of over 25, nearly one‐third of HCM patients demonstrated CMD in the LAD. Patients with LAD angio‐IMR > 25 exhibited a higher incidence of MACE compared to those with LAD angio‐IMR ≤ 25 (cumulative incidence, 25.4% vs. 13.3%, p = 0.035).
Yuxuan Zhang, Rui Ji, Shuxin Lei, Jingnan Pan, Zining Chen, Shitian Guo, Delong Chen, Abuduwufuer Yidilisi, Jiacheng Fang, Yiyue Zheng, Xinyi Zhang, Chi Liu, Jiniu Huang, Yumeng Hu, Jianping Xiang, Xiaojie Xie, Jian'an Wang, Jun Jiang   +17 more
wiley   +1 more source

Surgical Myectomy after Failed Ablation for Hypertrophic Obstructive Cardiomyopathy

The Thoracic & Cardiovascular Surgeon Reports, 2016
Background Hypertrophic cardiomyopathy is a genetic disease of the myocardial sarcolemma characterized by left ventricular hypertrophy. When obstruction to the left ventricular outflow tract is present and symptoms are refractory to medication, surgical ...
Ioannis Bougioukas, Uta Hoppe, Bernhard Danner, Friedrich A. Schoendube   +3 more
doaj   +1 more source

Prognosis in hypertrophic cardiomyopathy observed in a large clinic population [PDF]

, 1993
Overall annual cardiac mortality in hypertrophic cardiomyopathy (HC) has been reported to be between 2 and 4%, although these numbers are primarily from retrospective studies of patients referred to large research institutions. A clinic population of 113
Cate, F.J. (Folkert) ten, Kofflard, M.J.M. (Marcel), Vos, J. (Jeroen), Waldstein, D.J.   +3 more
core   +1 more source

Mitral Annulus Dynamics: Another Unmet Need in Valvular Heart Disease

Echocardiography, Volume 42, Issue 11, November 2025.
Paula Cristina Morariu, Mariana Floria, Diana‐Elena Floria, Daniela Maria Tanase   +3 more
wiley   +1 more source

Plasma big endothelin-1 predicts new-onset atrial fibrillation after surgical septal myectomy in patients with hypertrophic cardiomyopathy

BMC Cardiovascular Disorders, 2019
Background Postoperative atrial fibrillation (POAF) is a common complication in patients with obstructive hypertrophic cardiomyopathy (HOCM) who undergo surgical myectomy. POAF is associated with poor outcome. The role of plasma big endothelin-1 level in
Changpeng Song, Shengwei Wang, Ying Guo, Xinxin Zheng, Jie Lu, Xiaonan Fang, Shuiyun Wang, Xiaohong Huang   +7 more
doaj   +1 more source