Results 81 to 90 of about 107,014 (181)

Improvement in Left Ventricular Function of the Resected Myocardium after Septal Myectomy in Patients with Aortic Valve Replacement

Heart Surgery Forum
Background: Some surgeons have previously advocated for a more aggressive concomitant septal myectomy to address left ventricular outflow tract obstruction; however, concerns about the surgical complications of post-septal myectomy remain. Here, we aimed
Y. Kamikawa, S. Matsushita, S. Miyazaki, Ryoko Morimoto, Kenji Kuwaki, H. Inaba, Tohru Minamino, Atsushi Amano, Minoru Tabata   +8 more
semanticscholar   +1 more source

Prognostic Value of Coronary Angiography‐Derived Index of Microvascular Resistance in Patients With Hypertrophic Cardiomyopathy

MedComm, Volume 6, Issue 8, August 2025.
With an angio‐IMR threshold of over 25, nearly one‐third of HCM patients demonstrated CMD in the LAD. Patients with LAD angio‐IMR > 25 exhibited a higher incidence of MACE compared to those with LAD angio‐IMR ≤ 25 (cumulative incidence, 25.4% vs. 13.3%, p = 0.035).
Yuxuan Zhang, Rui Ji, Shuxin Lei, Jingnan Pan, Zining Chen, Shitian Guo, Delong Chen, Abuduwufuer Yidilisi, Jiacheng Fang, Yiyue Zheng, Xinyi Zhang, Chi Liu, Jiniu Huang, Yumeng Hu, Jianping Xiang, Xiaojie Xie, Jian'an Wang, Jun Jiang   +17 more
wiley   +1 more source

Concomitant Ozaki procedure and septal myectomy in patients with severe aortic stenosis

Siberian Journal of Clinical and Experimental Medicine
Objective. The presence of marked asymmetric septal hypertrophy in patients with aortic stenosis may lead to dynamic obstruction of the left ventricular outflow tract in addition to fixed obstruction at the level of the aortic valve.
E. E. Kobzev, I. A. Karpov, E. V. Rosseikin   +2 more
semanticscholar   +1 more source

Mitral Annulus Dynamics: Another Unmet Need in Valvular Heart Disease

Echocardiography, Volume 42, Issue 11, November 2025.
Paula Cristina Morariu, Mariana Floria, Diana‐Elena Floria, Daniela Maria Tanase   +3 more
wiley   +1 more source

Novel Techniques for Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy With Complex Anatomy: A Case Series

Catheterization and Cardiovascular Interventions, Volume 106, Issue 1, Page 349-354, July 1, 2025.
ABSTRACT Alcohol septal ablation (ASA) is an established treatment for hypertrophic obstructive cardiomyopathy (HOCM). However, conventional techniques may be challenging in cases with complex septal branch anatomy, including hairpin curves, extremely small branches, and acute angle bifurcations.
Junya Matsuda, Yukichi Tokita, Hitoshi Takano, Kuniya Asai   +3 more
wiley   +1 more source

Surgical management of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy [PDF]

, 2023
Introduction Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac condition affecting 1 in 500 of the population with a largely genetic autosomal dominant pattern of inheritance.
Collis, Richard
core  

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

ESC Heart Failure, Volume 12, Issue 3, Page 2321-2334, June 2025.
Abstract Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP) kinase (MAPK) pathway in severely affected RAS‐CM patients.
Jules Hamers, Payel Sen, Sarala Raj Murthi, Laura Papanakli, Maria von Stumm, Francesca Baessato, Julie Cleuziou, Christian Meierhofer, Peter Ewert, Andreas Dendorfer, Daphne Merkus, Cordula M. Wolf   +11 more
wiley   +1 more source

Clinical and genetic characterization of patients with hypertrophic cardiomyopathy and right atrial enlargement [PDF]

, 2016
AIMS: Prevalence and clinical significance of right atrial enlargement (RAE) has been poorly characterized in hypertrophic cardiomyopathy. METHODS: One hundred and sixty consecutive patients with hypertrophic cardiomyopathy (35.5 ± 20 years; 64% men ...
Bossone, E, Calabro, R, Elliott, P, Ferrara, I, Frisso, G, Gravino, R, Iacomino, M, Limongelli, G, Masarone, D, Pacileo, G, Rea, A, Salvatore, F   +11 more
core  

Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy [PDF]

, 2019
Hypertrophic cardiomyopathy is a genetic disorder of the myocardium, characterized by marked myocardial hypertrophy that may lead to the development of symptoms such as dyspnea, angina pectoris, or stress-induced syncopes, with an increased risk of ...
Comisso, Marina, Lio, Antonio, Musumeci, Francesco, Nicolo’, Francesca, Pantanella, Romina, Scrofani, Roberto   +5 more
core   +2 more sources

Alcohol septal ablation for obstructive hypertrophic cardiomyopathy [PDF]

, 2015
Hypertrophic cardiomyopathy is an inhered heart disease characterised by a thickened heart muscle, common in 1:500 persons. Obstruction of blood flow in the heart due the thickened heart muscle can occur and cause dyspnoea.
Steggerda, Robbert
core   +1 more source