Results 161 to 170 of about 40,994 (257)

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Shoulder Calcific Tendinitis Presenting as Septic Arthritis: A Case Report. [PDF]

Cureus
Aljumaan IM, Alzahrani AS, Khan HA, Alammar AAA, Alnakhli A.   +4 more
europepmc   +1 more source

Incidence and In‐Hospital Mortality of Ventricular Septal Rupture Following Acute Myocardial Infarction

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Ventricular septal rupture (VSR) is a rare but devastating complication of acute myocardial infarction (MI), associated with high mortality despite advances in reperfusion therapy. However, contemporary data examining national trends in VSR outcomes and the evolving role of mechanical circulatory support (MCS) in this population ...
Javier Fernandez, Namra Khan, Muni Rubens, Dorsa Majdpour, Masood Azhar, Mukesh Roy, Anshul Saxena, Sandra Chaparro, Javier Jimenez   +8 more
wiley   +1 more source

The prognostic implications of comorbidities in septic arthritis. [PDF]

Front Med (Lausanne)
Khudair A, Khudair A, Butler AE.
europepmc   +1 more source

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, EarlyView.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Trends in surgical management of septic arthritis of the knee: a 16-year observational study of 4,809 surgeries in Sweden. [PDF]

BMC Musculoskelet Disord
Schmidt V, Magnéli M, Axenhus M.
europepmc   +1 more source

A Comparison of Regional Decisions for Doses and Administrations of New Drugs: Concordance, Discordance, and Dependencies

Clinical Pharmacology &Therapeutics, EarlyView.
Regional differences in approved drug dosages and administration are shaped by complex factors, including clinical data, prior regulatory decisions, and region‐specific considerations. This study investigated how such factors are associated with variations in approved doses across the United States Food and Drug Administration (FDA), European Medicines
Sachiko Mita, Shunsuke Ono
wiley   +1 more source

Distinct clinical profiles of nongonococcal gram-negative septic arthritis: a retrospective analysis from a tertiary center. [PDF]

BMC Infect Dis
Niramaitaworn A, Meesing A, Pongkulkiat P, Manomaiwong N, Sribenjalux W.   +4 more
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source