Results 141 to 150 of about 303,388 (291)

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast

Transboundary and Emerging Diseases, Accepted Article., 2022
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann, Mikolaj Adamek, Dieter Steinhagen, Ralf Thiel   +3 more
wiley   +1 more source

Effects of Polyethylene Terephthalate Microplastics on Anaerobic Mono-Digestion and Co-Digestion of Fecal Sludge from Septic Tank. [PDF]

Molecules
Ma T, Liu N, Li Y, Ye Z, Chen Z, Cheng S, Campos LC, Li Z.   +7 more
europepmc   +1 more source

Innovative on-site soil disposal systems for septic tank effluent

, 1982
Innovative on-site soil disposal systems for septic tank ...
K Terkonda. Purush (7231091)
core   +1 more source

AI‐Assisted Morphometric Analysis and Molecular Phylogeny for a Dactylogyrid (Monopisthocotyla) Skin Parasite of an Ornamental Crenuchid Fish From Brazil

Acta Zoologica, EarlyView.
ABSTRACT This study presents a formal description and taxonomic appraisal of Cacatuocotyle adrianoi sp. n., a Neotropical parasite belonging to the family Dactylogyridae, integrating AI‐assisted morphometric analyses, molecular data, and phylogenetic reconstruction. Phylogenetic analyses recovered Cacatuocotyle adrianoi sp. n.
J. C. C. Aguiar, M. M. Osaki‐Pereira, N. G. Silva, P. D. Mathews, R. J. Silva   +4 more
wiley   +1 more source

Bioenergy-producing two-stage septic tank and floating wetland for onsite wastewater treatment: Circuit connection and external aeration. [PDF]

J Environ Manage
Saeed T, Al-Muyeed A, Zaman T, Hasan M, Ahmed T.   +4 more
europepmc   +1 more source

Understanding the transformation, speciation, and hazard potential of copper particles in a model septic tank system using zebrafish to monitor the effluent. [PDF]

ACS Nano, 2015
Lin S, Taylor AA, Ji Z, Chang CH, Kinsinger NM, Ueng W, Walker SL, Nel AE.   +7 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

A20 Inhibits IFN‐γ Signaling in Hepatocellular Carcinoma Cells by Binding to STAT1, Compromising Anti‐Tumor Immunity

Cancer Science, EarlyView.
A20 suppresses IFN‐γ signaling in HCC cells by binding to STAT1 through its ZnF7 domain, thereby reducing CXCL9, CXCL10, and HLA‐ABC expression, ultimately impairing CD8+ T‐cell‐mediated anti‐tumor immunity. ABSTRACT Immune checkpoint blockade (ICB) has demonstrated efficacy in clinical cancer therapy; however, a significant proportion of cancer ...
Yanlei Dong, Jing Yi, Ruoxuan Yang, Yingyue Wang, Zelong Ma, Hong Yuan, Meichen Song, Ying Xiao, Chun Guo, Jianing Wang, Xiaoyan Wang, Faliang Zhu, Lining Zhang, Yuchen Fan, Yongyu Shi   +14 more
wiley   +1 more source

Marine heatwave forecast triggers rapid response strategy for critically endangered red handfish

Conservation Science and Practice, EarlyView.
We demonstrate the value of proactive conservation in responding to climate extremes through Australia's first pre‐emptive rescue of a protected marine fish species, the Critically Endangered red handfish. Ahead of the 2023/2024 El Niño event, marine heatwave forecasts prompted the temporary removal of 25 red handfish from the wild.
Jemina Stuart‐Smith, Tyson J. Bessell, Alistair J. Hobday, Rick D. Stuart‐Smith, Ness Delpero, Victor Shelamoff, Scott D. Ling, Tara Kelly, Rachelle Hawkins, Helen Crawford, Ross Monash, Andrew J. Trotter   +11 more
wiley   +1 more source