Results 91 to 100 of about 421,170 (310)
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Advanced Science, EarlyView.Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
Could Inflammaging and Its Sequelae Be Prevented or Mitigated? [PDF]
, 2019 Aged humans display a chronic and low-grade inflammation, termed "inflammaging", which has been potentially linked to the subsequent development of some aging-associated systemic disorders, including type 2 diabetes, atherosclerotic cardiovascular ...
Elias, Peter M, Man, Mao-Qiang
core
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis [PDF]
, 2018 Background. The lead (Pb) exposure crisis in Flint, Michigan has passed from well-publicized event to a footnote, while its biological and social impact will linger for lifetimes.
Bayon, Baindu L. +3 more
core +2 more sources
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Brain damage following whooping cough vaccination : is it time to lay the myth to rest? [PDF]
, 1998 Whooping cough causes significant morbidity and mortality, especially in early infancy. Although an effective vaccine exists, vaccine uptake in Malta was previously disappointing due to the general public’s and the medical community’s doubts regarding ...
Busuttil, Ray, Grech, Victor E.
core
Return to school after brain injury [PDF]
, 2004 Objective: To examine return to school and classroom performance following traumatic brain injury (TBI) Design: Cross-sectional Setting: Community Subjects: 67 school-age children with TBI (35 mild, 13 moderate, 19 severe), and 14 uninjured matched ...
Hawley, Carol +3 more
core +1 more source
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Rheumatology Meets Rehabilitation: Post-Acute COVID-19 Sequelae Clinical Phenotypes and Targeted Care in Patients with Immune-Mediated Inflammatory Rheumatic Diseases [PDF]
Balneo and PRM Research JournalPost-acute coronavirus disease sequelae (PACS/long COVID) variably affects patients with immune-mediated inflammatory rheumatic diseases (IMIRDs), complicating accurate diagnosis and longitudinal care.
Andreea-Iulia Vlădulescu-Trandafir +10 more
doaj +1 more source
Behaviour and school performance after brain injury [PDF]
, 2004 Primary Objective: To examine the relationship between behavioural problems and school performance following traumatic brain injury (TBI) Methods and Procedures: Subjects: 67 school-age children with TBI (35 mild, 13 moderate, 19 severe), and 14 ...
Hawley, Carol
core +1 more source