Results 61 to 70 of about 288,924 (312)

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

open access: yesAdvanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang   +13 more
wiley   +1 more source

The cost of tuberculosis sequelae [PDF]

open access: yesEuropean Respiratory Journal, 2014
From the author: We thank A. Proano and co-workers for their important comments on our cost analysis of tuberculosis (TB) in the European Union [1]. As pointed out in our study, the cost calculation only refers to direct treatment costs of the disease itself under the implicit assumption that treatment success has either been gained over 24 months or,
openaire   +2 more sources

Sequelae of Major Trauma Patients with Maxillofacial Fractures

open access: yes, 2021
Objectives: Sequelae after maxillofacial fractures are frequent and may affect the patient’s quality of life. This study examined sequelae associated with maxillofacial fractures of severely traumatized patients focusing mainly on nerve injuries. Methods:
Petersen, Lasse Østrup   +4 more
core   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

[The sequelae of tuberculosis].

open access: yesKekkaku : [Tuberculosis], 1990
During the 20th century, tuberculosis has been the most prevalent and most harmful disease in Japan. Enormous medical researches have ever been performed to conquer the disease. Nevertheless tuberculosis has left various somatic and psychological residues on vast convalescents.
openaire   +2 more sources

Neurological sequelae in survivors of cerebral malaria

open access: yes, 2014
Introduction: Cerebral malaria is a common cause of neurological sequelae and death in childhood. Information on persistent neurological sequelae post hospital discharge and their predisposing factors are scarce.
Brown, BJ   +3 more
core   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

Sequelae of Arthrodesis of the Hip [PDF]

open access: yesJournal of the Royal Society of Medicine, 1980
Twenty-two patients with unilateral arthrodesis of the hip were reviewed clinically and radiologically ten years or more after operation. There was evidence of degenerative disease in 63.6% of the contralateral hips, 68.2% of the ipsilateral knees and in 59.1% of the contralateral knees. Both knees were affected in 50% of cases.
M E, Greiss, R J, Thomas, M A, Freeman
openaire   +2 more sources

A randomized controlled trial of coenzyme Q10 for fatigue in the late-onset sequelae of poliomyelitis

open access: yes, 2015
Objective: To determine if coenzyme Q10 alleviates fatigue in the late-onset sequelae of poliomyelitis. Design: Parallel-group, randomized, placebo-controlled trial.
Cooke, Marie   +10 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

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