Results 181 to 190 of about 4,228,228 (319)

Sequence-directed activation of human oncogenes.

, 1998
Sequence-directed activation of human ...
Lavanya. Lall (7958528)
core  

Radiomics-Guided Multi-Sequence Learning for Pathological Complete Response Prediction from Breast MRI with Missing Auxiliary Sequences. [PDF]

J Imaging
Xiang X, Yin W, Li J.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Sequencing Lung Cancer’s Sequence

American Journal of Respiratory and Critical Care Medicine, 2019
Watanabe, Hideo, Powell, Charles A.
openaire   +2 more sources

FeSseqdb: a curated sequence-level database and interpretable machine learning framework for identifying iron-sulfur proteins. [PDF]

BMC Bioinformatics
Min J, Brooks BR, Amin M.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Morse Sequences on Stacks and Flooding Sequences

This paper builds upon the framework of \emph{Morse sequences}, a simple and effective approach to discrete Morse theory. A Morse sequence on a simplicial complex consists of a sequence of nested subcomplexes generated by expansions and fillings-two operations originally introduced by Whitehead.
openaire   +2 more sources

EpiMII: Structure-Aware Graph Neural Networks for MHC-II Epitope Generation. [PDF]

Research (Wash D C)
Yuan J, Xu X, Sun ZY, Zhu S, Wei C, Liang T, Ge J, Xie XQ, Chen Y, Feng Z, Hou T, Xue Y.   +11 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Design and Implementation of Expressed Sequence Tag Alignment Tool

, 2009
[[abstract]]This thesis is to design the software, which can align the sequence of Express Sequence Tags database to its own genome. The main way is to implement Multi-Layer Unique Makers table, and use the concept of grid to reach distributed computing.
J. F. Chen
core