Results 271 to 280 of about 4,228,228 (319)

Searching for sequence features that control DNA cyclizability. [PDF]

PNAS Nexus
Gordiychuk M, Park J, Basu A, Ha T, Bialek W, Zhang Y.   +5 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

ADAPT: a programme for the advanced detection of AI-enabled pathogenic threats. [PDF]

Front Bioeng Biotechnol
Palya H, Nelson C.
europepmc   +1 more source

Large-scale statistical dissection of sequence-derived biochemical features distinguishing soluble and insoluble proteins. [PDF]

PLoS One
Vu NHH, Nguyen BL.
europepmc   +1 more source

ViralMultiNet: A structure-aware multimodal framework for viral protein function prediction in wastewater surveillance. [PDF]

PLoS One
Liu F, Lai T, Xu W, Li G.
europepmc   +1 more source

Heuristic multi-site optimization for protein sequence design using Masked Protein Language Models. [PDF]

PLoS Comput Biol
Wang L, Wang Y, Qiu C, Xiao L, Liu X, Chen J.   +5 more
europepmc   +1 more source

Correction: SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.

Elife
Chen XW, Wang H, Bajaj K, Zhang P, Ma D, Bai Y, Liu HH, Adams E, Baines A, Yu G, Sartor MA, Zhang B, Yi Z, Lin J, Young SG, Schekman R, Ginsburg D.   +16 more
europepmc   +1 more source

The Sequences and the Sequencers

Historical Studies in the Natural Sciences, 2022
This special issue on sequences and sequencers uses new analytical approaches to re-assess the history of genomics. Historical attention has largely focused on a few central characters and institutions: those that participated in the Human Genome Project (HGP), especially its final stages.
Rhodri Leng, Gil Viry, Miguel García-Sancho, James Lowe, Mark Wong, Niki Vermeulen   +5 more
openaire   +1 more source