Results 31 to 40 of about 3,080,122 (269)
Quantification of within-sample genetic heterogeneity from SNP-array data
Scientific Reports, 2017 Intra-tumour genetic heterogeneity (ITH) fosters drug resistance and is a critical hurdle to clinical treatment. ITH can be well-measured using multi-region sampling but this is costly and challenging to implement.
Pierre Martinez +5 more
doaj +1 more source
Variational-Like Inequality Problem Involving Generalized Cayley Operator
Axioms, 2021 This article deals with the study of a variational-like inequality problem which involves the generalized Cayley operator. We compare our problem with a fixed point equation, and based on it we construct an iterative algorithm to obtain the solution of ...
Zahoor Ahmad Rather +2 more
doaj +1 more source
On the boundary sequence of an automatic sequence
Discrete Mathematics, 2022 A `boundary' of a word \(w_i\cdots w_{i+n}\) over a finite alphabet is the word \(w_iw_{i+n}\), and the set of all boundaries of words of length \(n+1\) appearing in a sequence \(w=w_1w_2\cdots\) is denoted \(\partial_{w}(n)\), giving a `boundary sequence' \((\partial_w(n))_{n\ge 1}\) associated to \(w\). \textit{J. Chen} and \textit{Z.-X. Wen} [Theor.
Yingjun Guo, Xiao-Tao Lü, Zhi-Xiong Wen
openaire +1 more source
Advanced Science, 2020 Like many important crops, peanut is a polyploid that underwent polyploidization, evolution, and domestication. The wild allotetraploid peanut species Arachis monticola (A.
Dongmei Yin +27 more
doaj +1 more source
Microorganisms, 2022 Herein, we report a case of an Italian male infected by Delta sublineage AY.4 harboring an atypical deletion, leading to a N gene target failure (NGTF) by a commercial molecular assay for SARS-CoV-2 diagnosis (AllplexTM SARS-CoV-2 Assay, Seegene).
Mohammad Alkhatib +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Frontiers in Microbiology, 2017 Product-releasing enzyme (PRE) domains in fungal non-reducing polyketide synthases (NR-PKSs) play a crucial role in catalysis and editing during polyketide biosynthesis, especially accelerating final biosynthetic reactions accompanied with product ...
Lu Liu +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
Genetic Polymorphism and Association of KAP16.6 Gene with Pashmina Fiber Traits in Changthangi Goats
Journal of Natural Fibers, 2022 Pashmina is the fine undercoat of the Changthangi goats (Capra hircus) with Keratin-associated proteins (KAPs) as one of its main structural components. KAPs form a semi-rigid matrix in which the Keratin intermediate filaments (KIFs) are embedded. In the
Syed Shanaz +5 more
doaj +1 more source