Results 331 to 340 of about 31,098,092 (376)

MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets

open access: yesNature Biotechnology, 2017
VOLUME 35 NUMBER 11 NOVEMBER 2017 NATURE BIOTECHNOLOGY performance was to combine the doublematch criterion with making k-mers as long as possible, which required finding similar and not just exact k-mers. This effectively bases our decision on up to 2 ×
Martin Steinegger, Johannes Söding
exaly   +2 more sources

Sequence Analysis on Microcomputers

Science, 1987
Overall, each of the program packages performed their tasks satisfactorily. For analyses where there was a well-defined answer, such as a search for a restriction site, there were few significant differences between the program sets. However, for tasks in which a degree of flexibility is desirable, such as homology or similarity determinations and ...
openaire   +2 more sources

Analysis of DNA sequences

Statistical Methods in Medical Research, 1993
Recent developments in the statistical analysis of DNA sequences are reviewed. The pace with which sequence data are being generated and analysed has increased with the growth of the human genome project. Two areas of activity are emphasized: attention to error rates in recorded sequences, and heterogeneity in structure of sequences.
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Advances in sequence analysis

Current Opinion in Structural Biology, 2001
In its early days, the entire field of computational biology revolved almost entirely around biological sequence analysis. Over the past few years, however, a number of new non-sequence-based areas of investigation have become mainstream, from the analysis of gene expression data from microarrays, to whole-genome association discovery, and to the ...
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RNA SEQUENCE ANALYSIS

Annual Review of Biochemistry, 1970
FRACTIONATION AND PURIFICATION OF RNA 228 Transfer RNA 228 Ribosomal RNA ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. 230 Viral RNA 230 SEPARATION AND ISOLATION OF POLYNUCLEOTIDES 231 Physical methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Peptide Sequence Analysis

2005
In mass spectrometry (MS)-based protein studies, peptide fragmentation analysis (i.e., MS/MS experiments such as matrix-assisted laser desorption ionization [MALDI]-post-source decay [PSD] analysis, collision-induced dissociation [CID] of electrospray- and MALDI-generated ions, and electron-capture and electron-transfer dissociation analysis of ...
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COMPUTATIONAL ANALYSIS OF GENETIC SEQUENCES

Annual Review of Biophysics and Biophysical Chemistry, 1986
Much computational processing of sequence data can be accomplished by applying the kinds of computational tools and processes widely used in text processing, perhaps specialized to sequences, but not necessarily so. A number of programs have been developed specifically to assist in assembling sequences from individually sequenced restriction fragments.
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Nucleotide sequence analysis of DNA

Journal of Molecular Biology, 1970
There are three major obstacles to the analysis of the nucleotide sequence in a DNA molecule starting from a known location in the DNA molecule. First, it is difficult to obtain large quantities of homogeneous DNA. Second, even the smallest DNA molecules contain several thousand nucleotides which make sequence analysis prohibitive.
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Sequence Handling by Sequence Analysis Toolbox v1.0

2006
The fact that mass spectrometry have become a high-throughput method calls for bioinformatic tools for automated sequence handling and prediction. For efficient use of bioinformatic tools, it is important that these tools are integrated or interfaced with each other.
Ingrell, Christian Ravnsborg   +2 more
openaire   +3 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

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