Results 221 to 230 of about 5,758,485 (356)

Author Correction: Combinatorial selective ER-phagy remodels the ER during neurogenesis. [PDF]

open access: yesNat Cell Biol
Hoyer MJ   +11 more
europepmc   +1 more source

Overview of MicroRNA Biology

open access: yesSeminars in liver disease (Print), 2015
Ashley M. Mohr, J. Mott
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Monkeyflower (Mimulus) uncovers the evolutionary basis of the eukaryote telomere sequence variation. [PDF]

open access: yesPLoS Genet
Kumawat S   +13 more
europepmc   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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