Results 221 to 230 of about 5,842,285 (378)

Bridging The Chromosome-Centric And Biology And Disease Human Proteome Projects: Accessible And Automated Tools For Interpreting Biological And Pathological Impact Of Protein Sequence Variants Detected Via Proteogenomics

, 2018
Ray Sajulga, Subina Mehta, Praveen Kumar, James E. Johnson, Candace R. Guerrero, Michaël Ryan, Rachel Karchin, Pratik Jagtap, Timothy J. Griffin   +8 more
openalex   +2 more sources

Book Review: Algorithms on strings, trees, and sequences: computer science and computational biology by Dan Gusfield (: Cambridge University Press, Cambridge, England, 1997) [PDF]

, 1998
Gary Benson
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Competition and cooperation of assembly sequences in recurrent neural networks. [PDF]

PLoS Comput Biol
Stöber TM, Lehr AB, Nikzad A, Ganjtabesh M, Fyhn M, Kumar A.   +5 more
europepmc   +1 more source

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

, 2019
Adam J. Kleinschmit, Benita Brink, Steven Roof, Carlos Goller, Sabrina D. Robertson   +4 more
openalex   +1 more source

High Levels of Sequence Polymorphism and Linkage Disequilibrium at the Telomere of 12q: Implications for Telomere Biology and Human Evolution [PDF]

, 2000
Duncan M. Baird, Joanna Coleman, Zoë H. Rosser, Nicola J. Royle   +3 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

RNAtranslator: Modeling protein-conditional RNA design as sequence-to-sequence natural language translation. [PDF]

PLoS Comput Biol
Shukueian Tabrizi S, Barazandeh S, Hashemi Aghdam H, Cicek AE.   +3 more
europepmc   +1 more source

Overview of MicroRNA Biology

Seminars in liver disease (Print), 2015
Ashley M. Mohr, J. Mott
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source