Results 281 to 290 of about 1,220,765 (311)

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

AUGcontext DB: a comprehensive catalog of the mRNA AUG initiator codon context across eukaryotes. [PDF]

open access: yesRNA Biol
Osnaya VG   +3 more
europepmc   +1 more source

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

open access: yesFEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla   +4 more
wiley   +1 more source

Patient-centric analysis of Orientia tsutsugamushi spatial diversity patterns across Hainan Island, China. [PDF]

open access: yesPLoS Negl Trop Dis
Tang C   +22 more
europepmc   +1 more source

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