Results 171 to 180 of about 8,102,704 (303)
, 2018 Comparison of previously described innexin sequence identity and expression against CNS transcriptome.
Adam J. Northcutt (5540906) +4 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Optical pattern generator for efficient bio-data encoding in a photonic sequence comparison architecture. [PDF]
PLoS One, 2021 Akbari Rokn Abadi S +2 more
europepmc +1 more source
Sequence comparison significance and poisson approximation
, 1994 . The Chen-Stein method of Poisson approximation has been used to establish theorems about comparison of two DNA or protein se-quences. The most usefil result for sequence alignment applies to align-ment scoring with no gaps.
Martin Vincron +2 more
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A new approach to compare the scientific impact of scholars
Journal of Data and Information ScienceGenerally, the scientific comparison has been done with the help of the overall impact of scholars. Although it is very easy to compare scholars, but how can we assess the scientific impact of scholars who have different research careers?
Bihari Anand +3 more
doaj +1 more source
Application of Highly Flexible Adaptive Image Receive Coil for Lung MR Imaging Using Zero TE Sequence: Comparison with Conventional Anterior Array Coil. [PDF]
Diagnostics (Basel), 2022 Bae K, Jeon KN, Hwang MJ, Jung Y, Lee J.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source