Results 231 to 240 of about 104,871 (266)

Molecular epidemiological characteristics of coxsackievirus A6 in Jinhua, China, 2019-2023. [PDF]

Sci Rep
Sun P, Pang Z, Zhang B, Zhu J, Wu B, Wang J, Yao X, Zhu S.   +7 more
europepmc   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

dMMR killer: A conditional suicide gene that preferentially kills DNA mismatch repair-deficient cells. [PDF]

Mol Ther Nucleic Acids
Saito S, Kato S, Arai U, Tateishi K, Adachi N.   +4 more
europepmc   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

Subtype-specific functions of basal IFNλs. [PDF]

J Virol
Stanifer ML.
europepmc   +1 more source

How Do DICER1 Syndrome Mutations Disrupt Catalysis? Unveiling Dicer Metal Binding Architecture and Mechanism of Action Using MD Simulations and QM/MM Calculations

Journal of Computational Chemistry, Volume 47, Issue 18, July 5, 2026.
Dicer plays a vital role in gene regulation, making understanding its function critical for drug design and addressing human diseases. This article uses a combination of MD and QM/MM techniques to elucidate structural details of the Dicer–substrate complex, the Dicer catalytic mechanism, and the misfunction of DICER1‐syndrome‐causing mutants.
Dylan J. Nikkel, Stacey D. Wetmore
wiley   +1 more source

Rational design of mechanically active RNAs: de novo engineering of functional exoribonuclease-resistant RNAs. [PDF]

Nucleic Acids Res
Walter J, Sidl L, Gutenbrunner K, Skibinski D, Kolberg T, Hofacker IL, Yao HT, Mörl M, Wolfinger MT.   +8 more
europepmc   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Assembly of the Linear Viral Nucleocapsid. [PDF]

Microorganisms
Luo M, Lyles KV, Faniyi OO, Kim R.
europepmc   +1 more source

Virome of canine lymph nodes: identification of viruses with zoonotic potential. [PDF]

Virol J
Huang S, Chen Y, Lu X, Ji L, Shen Q, Yang S, Liu Y, Wang X, Wu P, Yang H, Shan T, Zhang W.   +11 more
europepmc   +1 more source