Results 241 to 250 of about 8,935,685 (345)

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Using Evolutionary Algorithms and Machine Learning to Explore Sequence Space for the Discovery of Antimicrobial Peptides

, 2018
Mari Yoshida, T. Hinkley, S. Tsuda, Yousef M. Abul-Haija, Roy T. McBurney, V. Kulikov, Jennifer S. Mathieson, Sabrina Galiñanes Reyes, M. Castro, L. Cronin   +9 more
semanticscholar   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Exploring the energetic and conformational properties of the sequence space connecting naturally occurring RNA tetraloop receptor motifs. [PDF]

RNA
Shin JH, Cuevas LM, Roy R, Bonilla SL, Al-Hashimi H, Greenleaf WJ, Herschlag D.   +6 more
europepmc   +1 more source

Exploring the sequence space for (tri-)peptide self-assembly to design and discover new hydrogels.

Nature Chemistry, 2015
Pim W. J. M. Frederix, Gary G. Scott, Yousef M. Abul-Haija, Daniela Kalafatovic, Charalampos G. Pappas, Nadeem Javid, N. T. Hunt, R. Ulijn, T. Tuttle   +8 more
semanticscholar   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

A percolation theory analysis of continuous functional paths in protein sequence space affirms previous insights on the optimization of proteins for adaptability. [PDF]

PLoS One
Miller BJ.
europepmc   +1 more source

Mapping membrane activity in undiscovered peptide sequence space using machine learning

Proceedings of the National Academy of Sciences of the United States of America, 2016
Ernest Y Lee, Benjamin M Fulan, Gerard C. L. Wong, Andrew L. Ferguson   +3 more
semanticscholar   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Exploring the compatibility of phosphopantetheinyl transferases with acyl carrier proteins spanning type II polyketide synthase sequence space. [PDF]

J Ind Microbiol Biotechnol
Bifendeh ALN, Hsu KK, McBride CM, Ferguson CM, Baumann ER, Capcha-Rodriguez D, Chen X, Chery B, Chihade MM, Umpierre PD, Evans T, Everett CH, Faheem SF, Garrett OD, Gottesfeld AR, Gupta IG, Haas JD, Haupt TA, Katz J, Kim S, Langer M, Le V, Li KK, Zhao B, Lin S, Mabry KN, Malkov A, Marquis AT, McDonnell KR, Min K, Mostaghim NB, Nichols KM, Osbaldeston RA, Phan TT, Ponte AT, Qaraqe T, Rosas BS, Smith CS, Smith LE, Smith MW, Soll ACR, Sotero GR, Thornberry IE, Tran K, Vo QK, Yoc-Bautista MG, Young M, Zukowski KA, Fairman R, Wodzanowski KA, Herrera MA, Cho YI, Charkoudian LK.   +52 more
europepmc   +1 more source