Results 141 to 150 of about 8,296,713 (306)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Some normed binomial difference sequence spaces related to the [Formula: see text] spaces. [PDF]

J Inequal Appl, 2017
Song M, Meng J.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Weighted Sequence Spaces and Cyclicity

Journal of Mathematical Extension, 2006
In this paper we investigate the cyclicity of the multiplication operator Mz acting on the weighted Hardy spaces of formal Laurent series. AMS Subject Classification: Primary 47B37; Secondary 47A16.
J. Doroodgar, B. Yousefi
doaj  

Exact correspondence between walk in nucleotide and protein sequence spaces. [PDF]

PLoS One, 2017
Ivankov DN.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Orlicz-Garling sequence spaces of difference operator and their domination in Orlicz-Lorentz spaces. [PDF]

J Inequal Appl, 2018
Sharma C, Mohiuddine SA, Raj K, Alkhaldi AH.   +3 more
europepmc   +1 more source

p_Hahn Sequence Space

, 2014
8 ...
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

On Orlicz Difference Sequence Spaces

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2010
: The main aim of this article is to generalize the famous Orlicz sequence space by using difference operators and a sequence of non-zero scalars and investigate some topological structure relevant to this generalized space.
Hemen Dutta
doaj