Results 181 to 190 of about 3,312,497 (352)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Assessment of long-read strategies for the enrichment of clinically relevant breakpoints in lymphomas: towards a diagnostic implementation. [PDF]

Ann Hematol
Pardy F, Reblova K, Svozilova H, Tichy B, Pospisilova S, Kotaskova J, Navrkalova V.   +6 more
europepmc   +1 more source

Sequencing and sequence analysis of partial nucleoprotein (N) gene and phylogenetic analysis of rabies virus field isolates from Gujarat state, India [PDF]

, 2017
Dhaval H. Vagheshwari, B. B. Bhanderi, Rafyuddin A. Mathakiya, Mayurdhvaj K. Jhala   +3 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

cuteSV-OL: a real-time structural variation detection framework for nanopore sequencing devices. [PDF]

Bioinformatics
Guo W, Liu Y, Wang Y, Jiang T.
europepmc   +1 more source

Sequencing cell-type-specific transcriptomes with SLAM-ITseq

, 2019
Wayo Matsushima, Veronika A. Herzog, Tobias Neumann, Katharina Gapp, Johannes Zuber, Stefan L. Ameres, Eric A. Miska   +6 more
openalex   +2 more sources

Democratizing sequencing [PDF]

Nature Methods, 2005
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Detection of Rare Thalassemia Variants Using Accurate Circular Consensus Long-Read Sequencing. [PDF]

Hum Mutat
Zhou X, Chen Y, Chen S, Lian J, Liu Y, Yang T, Wu S, Liu J, Huang X, Yang X.   +9 more
europepmc   +1 more source

Sequencing spinning lines [PDF]

, 2002
Gravesen, J., Noble, S.
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