Results 221 to 230 of about 3,312,497 (352)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Development of an APC and TP53-based duplex sequencing assay to positively predict colorectal cancer response to anti-EGFR therapy. [PDF]

Cell Oncol (Dordr)
Yang M, Schell MJ, Salk JJ, Higgins J, Hipp M, Pflieger L, Pledger WJ, Yeatman TJ.   +7 more
europepmc   +1 more source

Top‐down ion mobility/mass spectrometry reveals enzyme specificity: Separation and sequencing of isomeric proteoforms

Francis Berthias, Nurgül Bilgin, Jasmin Mecinović, Ole N. Jensen   +3 more
openalex   +2 more sources

Whole Genome-Sequencing and Phylogenetic Analysis of Bacillus anthracis from 2019–2023 in Ningxia Hui Autonomous Region, China [PDF]

Ran Xian, Cong Yang, Jianwei Gao, Xiang Liu, Qian Chen, Lei Gao, Zhao Yu, Wenhe Kuai, Jiangtao Ma   +8 more
openalex   +1 more source

523 Disease-targeted next generation sequencing identifies mutations in consanguineous families with phenotypic spectrum of ichthyoses [PDF]

, 2017
Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Sirous Zeinali, Soheila Sotoudeh, Hamidreza Mahmoudi, Parvin Mansouri, Maryam Daneshpazhooh, Paolo Fortina, J. Uitto   +9 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Targeted long-read nanopore sequencing as a complementary approach for detecting STRC variants and distinguishing the STRCP1 pseudogene. [PDF]

Sci Rep
Moteki H, Nishio SY, Usami SI.
europepmc   +1 more source

Rotameter sequence [PDF]

Anaesthesia, 1996
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Optimising Genome-Wide Detection of Runs of Homozygosity: Impacts of Reference Genome Quality and Sequencing Parameters on Inbreeding Assessment. [PDF]

Mol Ecol Resour
Shi M, Li H, Shafer ABA, Lan T.
europepmc   +1 more source