Results 151 to 160 of about 1,414,860 (296)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly +7 more
wiley +1 more source
Batch‐to‐Batch Optimization of pH Shifts in CHO Bioreactor Operations
Biotechnology and Bioengineering, EarlyView.ABSTRACT Culture pH is an important operating parameter in CHO cell cultures producing mAb since it directly affects growth and specific productivity. Mathematical models can be used to optimize the magnitude and timing of pH shifts provided that they are robust to model errors.
Ali Ghodba +6 more
wiley +1 more source
A Modular Micro‐Chemostat System for High‐Throughput Continuous Cultivations
Biotechnology and Bioengineering, EarlyView.This study presents and demonstrates a modular 12‐channel micro‐chemostat, designed to be used by Genesis, a Robot Scientist developed to automate scientific research in yeast systems biology. The bioreactor performance fulfilled the predefined requirements, and the empirical results from the biological experiments were consistent with the literature ...
Erik Y. Bjurström +7 more
wiley +1 more source
Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry
Bulletin of the Korean Chemical Society, EarlyView.Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah +8 more
wiley +1 more source
工程科学与技术, 2008 :In order to improve the efficiency of biological treatment of living sewage with rich nitrogen and phosphorus, and reduce the carbon source, the character of simultaneous nitrification and denitrification and biological phosphorus removal of ...
doaj
Biochemistry and Molecular Biology Education, EarlyView.ABSTRACT Low‐cost experiential modules are critical for democratizing biotechnology education, yet most undergraduates lack hands‐on experience with continuous‐culture bioreactor operations, which are fundamental to industrial bioprocessing. This study employed design‐based research across two iterative cycles (Fall 2024, n = 8; Fall 2025, n = 11) to ...
Russell K. Pirlo +2 more
wiley +1 more source
Regeneration of activated carbon by fenton and photofenton oxidation for the treatment of phenol wastewater [PDF]
, 2009 Advanced Oxidation Processes have emerged as promising technologies for the recovery of carbons saturated with aromatic molecules, owing to their potency to degrade a wide range of organic pollutants by the generation of very reactive and non selective ...
Wilhelm, Anne-Marie +4 more
core
BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng +4 more
wiley +1 more source
Scalable catalyst production process for oleate hydratase whole‐cell biocatalysis
Biotechnology Progress, EarlyView.This study establishes a scalable lactose‐induced fed‐batch fermentation for an Escherichia coli whole‐cell biocatalyst containing an oleate hydratase. Operation at a higher growth rate markedly increased biomass yields while maintaining catalyst activity and was demonstrated at 150 L scale.
Rebekka Horstmann +6 more
wiley +1 more source
Sequencing batch reactor performance treating PAH contaminated lagoon sediments
, 2005 The applicability of sediment slurry sequencing batch reactors (SBR) to treat Venice lagoon sediments contaminated by polycyclic aromatic hydrocarbons (PAHs) was investigated, carrying out experimental tests.
Stante, L., Giordano, A.
core +1 more source