Results 151 to 160 of about 1,912,124 (266)

Association of torque teno virus in periodontitis: a systematic review, meta-analysis, and trial sequential analysis. [PDF]

Front Oral Health
Chauca-Bajaña L, Pérez-Sayáns M, Lorenzo-Pouso AI, Velasquez-Ron B, Erazo Vaca RX, Dau Villafuerte RF, Maroto Hidalgo VN, Narváez Guerrero JT, Palacios Jurado CH, Castellano MT, Ordóñez Balladares A.   +10 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta-Analysis and Trial Sequential Analysis. [PDF]

Cardiovasc Ther
Wang S, Li C, Fan D.
europepmc   +1 more source

Sequential Analysis [PDF]

Nature, 1948
openaire   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Imaging and Clinical Outcomes with Sentinel Cerebral Embolic Protection During TAVR: A Meta-Analysis of Randomized Trials with Trial Sequential Analysis. [PDF]

J Clin Med
Pavan Lingamsetty SS, Kritya M, Vatsavayi P, Tera CR, Doma M, Jitta SR, Gudiwada MCVB, Jasti J, Ramadan A, Vedantam V, Villablanca PA, Goldsweig AM.   +11 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Use of albumin in patients with hepatic encephalopathy: A systematic review and meta-analysis of randomized controlled studies with trial sequential analysis. [PDF]

Hepatol Forum
Coan ACC, Vanio Livramento Junior A, Prata AA, Milioli NJ, Correa TL, Martins OC, Romeiro P, Júnior ESB, Reis AM, Fernandes MV.   +9 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Intranasal dexmedetomidine for perioperative sleep disturbance: a protocol for a systematic review with meta-analysis and trial sequential analysis. [PDF]

BMJ Open
Liu D, Huang Y, Du L, Zhang W, Li T, Zheng J.   +5 more
europepmc   +1 more source