Results 171 to 180 of about 527,248 (278)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Sequential Extraction and <i>In Vitro</i> Bioactivities of Polysaccharides Fraction from Mung Bean Meal Byproduct. [PDF]

ACS Omega
Aiamsung M, Tabtimmai L, Bunphueak P, Sonklin C, Wisetsai A, Choowongkomon K, Sedtananun S.   +6 more
europepmc   +1 more source

Accumulation and fractionation of trace metals in a Tunisian calcareous soil amended with farmyard manure and municipal solid waste compost [PDF]

, 2010
Ben Achiba, W, Boeckx, Pascal, Du Laing, Gijs, Gabteni, Noureddine, Gallali, Tahar, Jedidi, Naceur, Lakhdar, Abdelbasset, Van Cleemput, Oswald, Verloo, Marc   +8 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Correction to: Nickel dynamics and immobilization in soil‑bauxite residue systems: insights from sequential extraction and FTIR analysis. [PDF]

Environ Sci Pollut Res Int
Zafeiriou I, Ioannou D, Angelopoulos P, Georgiou E, Gasparatos D, Massas I.   +5 more
europepmc   +1 more source

Integrated Assessment of Affinity to Chemical Fractions and Environmental Pollution with Heavy Metals: A New Approach Based on Sequential Extraction Results. [PDF]

Int J Environ Res Public Health, 2021
Vodyanitskii Y, Vlasov D.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Application of Sequential Extraction Using Pressurized Fluids to Obtain Compounds from <i>Pereskia aculeata</i> Leaves. [PDF]

Plants (Basel)
Passos FRD, Fiorese ML, Silva EAD, Oliveira Santos Junior O, Cardozo-Filho L, Silva CD.   +5 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Expanding the pH-Shift Technique for Sequential Extraction of Intact Proteins and Sulfated Polysaccharide From Fish Heads: A Novel Biorefinery Approach. [PDF]

Food Sci Nutr
Naghdi S, Rezaei M, Tabarsa M, Abdollahi M.   +3 more
europepmc   +1 more source