Results 111 to 120 of about 14,528 (304)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

open access: yesAdvanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang   +16 more
wiley   +1 more source

Study on Visual Techniques of Potential Pattern Discovery for Time Series Data

open access: yesMATEC Web of Conferences, 2018
Sequential pattern mining is always a very important branch of time series data mining. The pattern mining with visual means can be used to extract the knowledge of time series data more intuitively. Based on the research content, this paper analyzes the
Xu Dalin, Wei Yingmei
doaj   +1 more source

Discover Sequential Patterns in Incremental Database

open access: yes, 2013
The task of sequential pattern mining is to discover the complete set of sequential patterns in a given sequence database with minimum support threshold.
Lin, Nancy P.; Hao, Wei Hua; Chen, Hung Jen; Chueh, Hao En; Chang, Chung I
core  

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

open access: yesAdvanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin   +11 more
wiley   +1 more source

Generative AI‐Driven Accelerated Discovery of Passivation Molecules for Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
A generative artificial intelligence (AI) framework combining a discriminative machine learning model (SMILES‐X) and a generative language model (GPT‐2) autonomously discovers new molecular passivators for perovskite solar cells (PSCs). Through an iterative design loop, over 100 000 candidates are generated and screened, and randomly selected molecules
Adroit T. N. Fajar   +7 more
wiley   +1 more source

Parallel sequential pattern mining on distributed system

open access: yes, 2010
碩士本研究以提昇循序樣本探勘效率為目標,發展了一套結合多部電腦的分散式探勘系統。首先,由於直接以支持度預測子任務工作量並不準確,我們提出新的工作量預測方法。而後,本研究提出了一套負載平衡演算法-ADLB,結合動態與靜態分配的特點,對於任務採取分段分配,以達成負載平衡並降低通訊負擔。此外,我們也引用並改進文獻[20]中有關演算法切換的概念,以取得更大幅度效能改善。為驗證系統效能,我們結合了16部電腦進行分散式探勘,實驗結果顯示,本系統在各種不同節點數目下均具有良好加速比,顯示其具有處理大型資料之潛力 ...
郭家君; Guo, Jia-jyun
core  

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

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