Results 161 to 170 of about 43,818 (298)

Nonsmooth sequential analysis in Asplund spaces

, 1996
We develop a generalized differentiation theory for nonsmooth functions and sets with nonsmooth boundaries defined in Asplund spaces. This broad subclass of Banach spaces provides a convenient framework for many important applications to optimization ...
Mordukhovich, B.S., Shao, Y.
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Built environment effects on older adults' health mediated by leisure activities and social participation in Dong settlements of Western Hunan. [PDF]

Sci Rep
Luo Y, Liu X, Wang Q, Gu M, Li Y, Luo W.
europepmc   +1 more source

A multimodal social semiotic approach to the analysis of manga : a metalanguage for sequential visual narratives

, 2009
Includes abstract.Includes bibliographical references (p. 139-143).This study contributes towards an understanding of the nature of sequential visual narratives, how different semiotic resources may be employed to construct a visual narrative and how ...
Huang, Cheng-Wen
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

On Some Categories Of Sequential Spaces

, 1995
. The sequential spaces dealt with in the paper have arbitrary ordinals as domains of sequences and are subjected, besides the axiom of convergence of constant sequences, to only one other, quite special axiom.
Josef Slapal
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Parametrized Graph Convolutional Multi-Agent Reinforcement Learning with Hybrid Action Spaces in Dynamic Topologies. [PDF]

Biomimetics (Basel)
Chi P, Liu C, Zhao J, Wang Y.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The SPA-cube framework: An integrated approach for analysing power dynamics in environmental governance. [PDF]

MethodsX
Sahide MAK, Siswandi S, Sirimorok N, Fisher MR, Wong GY, Brockhaus M.   +5 more
europepmc   +1 more source