Results 191 to 200 of about 454,692 (339)

Designer Solid Self‐Emulsifying Nanovaccines Enable Dual Modulation of Dendritic Cells and T Cells for Potent Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen   +8 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Remote Modulation of Single‐Atom Catalyst Boosts High‐Valent Cobalt–Oxo Species Generation for Water Purification and Detoxification

open access: yesAdvanced Science, EarlyView.
This study develops a phosphorus‐doped cobalt single‐atom catalyst that enhances high‐valent cobalt–oxo species generation for water purification. This atomic‐level tuning boosts the catalyst's activity by 3.5 times, enabling efficient pollutant degradation. A continuous‐flow reactor achieves high, long‐term removal efficiency, producing water with low
Wen‐Min Wang   +4 more
wiley   +1 more source

Effects of Extracorporeal Membrane Oxygenation Circuits on Drug Sequestration: A Review of Ex Vivo Experiments. [PDF]

open access: yesJ Clin Med
Bertin S   +9 more
europepmc   +1 more source

U.S. Department of Energy’s Regional Carbon Sequestration Partnership Program: Overview

open access: diamond, 2009
John Litynski   +8 more
openalex   +1 more source

Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy

open access: yesAdvanced Science, EarlyView.
Idiopathic pulmonary fibrosis (IPF) progression is driven by TGF‐β induced biochemical signals and mechanical signals from increased ECM stiffness. Pulmonary‐targeted VB‐RT NPs not only eliminate excessive ROS and penetrate the dense ECM collagen barrier via NO release, but also simultaneously interrupt the persistent malignant between mechanical and ...
Xue‐Na Li   +11 more
wiley   +1 more source

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