Results 231 to 240 of about 554,010 (389)

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Preoperative embolization of dual arterial supply in extralobar pulmonary sequestration: a case report and literature review. [PDF]

CVIR Endovasc
Gad S, Mohnasky M, Kokabi N, Schrank Z, Evans A, Haithcock B, O'Hara D, Brown P, Caddell A, Goddard C, Gholami B, Afrasiabi A, Villalobos A.   +12 more
europepmc   +1 more source

Numerical Simulation of Gas Absorption-Expansion Dynamics in Abandoned Mine Carbon Sequestration Reservoirs

Ruijng Su, Yanli Huang, Junmeng Li, Jiachen Liu, Jianxiang Xu, Qihang Li, Shenyang Ouyang   +6 more
openalex   +1 more source

Climate change, human impacts, and carbon sequestration in China

Proceedings of the National Academy of Sciences of the United States of America, 2018
Jingyun Fang, Jingyun Fang, Guirui Yu, Lingli Liu, Shuijin Hu, Shuijin Hu, F. Chapin   +6 more
semanticscholar   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

How cells tame noise while maintaining ultrasensitive transcriptional responses. [PDF]

PLoS Comput Biol
Jeong EM, Chung CY, Kim JK.
europepmc   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Beyond Hypertrophy: A Case of Mid-ventricular Obstructive Hypertrophic Cardiomyopathy With Apical Sequestration. [PDF]

Cureus
Taoussi O, Scadi S, Mokhtari M, Benouna G, Merzouk F.   +4 more
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Effects of Extracorporeal Membrane Oxygenation Circuits on Drug Sequestration: A Review of Ex Vivo Experiments. [PDF]

J Clin Med
Bertin S, Haefliger D, Schneider AG, Giraud R, Perez MH, Bechtold X, Di Paolo ER, Rothuizen LE, Buclin T, Livio F.   +9 more
europepmc   +1 more source