Results 41 to 50 of about 9,633,644 (314)
, 2020 Multitasking optimization is a recently introduced paradigm, focused on the simultaneous solving of multiple optimization problem instances (tasks). The goal of multitasking environments is to dynamically exploit existing complementarities and synergies ...
Del Ser, Javier +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Arthritis Research & Therapy, 2020 Objectives To assess whether age, at the beginning of biologic treatment, is associated with the time a first adverse event (AE) appears in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), or psoriatic arthritis (PsA).
Paloma Vela +14 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Frontiers in Psychology, 2023 Many symptoms of the autism spectrum disorder (ASD) are evident in early infancy, but ASD is usually diagnosed much later by procedures lacking objective measurements.
Maria Eleonora Minissi +9 more
doaj +1 more source
Ser japonês, ser nikkei, ser dekassegui
Revista de Antropologia da UFSCar, 2014 O •luxo transnacional de brasileiros para o Japão trouxe várias disrupções dentro das comunidades nikkei espalhadas pelo Brasil, mas, mais do que isso: contorce e dobra planos hierárquicos seculares. Ancorado na lógica familiar do ie por vários séculos e aliando-se à incorporação dessa lógica com a fabricação da cidadania japonesa, temos no processo ...
openaire +2 more sources
Derechos en Acción, 2020 El estudio que aquí se presenta se basa en el análisis crítico de la sentencia que condenó a cadena perpetua Reina Maraz Bejarano (en adelante RM) por el delito de homicidio agravado por el vínculo, para referirme luego a la sentencia que la absolvió.
openaire +2 more sources
McShane's Identity in Rank One Symmetric Spaces
, 2012 In this paper we study McShane's identity in real and complex hyperbolic spaces and obtain various generalizations of the identity for representations of surface groups into the isometry groups of rank one symmetric spaces.
Kim, Inkang +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Optimal Phase Swapping in Low Voltage Distribution Networks Based on Smart Meter Data and Optimization Heuristics [PDF]
, 2017 In this paper a modified version of the Harmony Search algorithm is proposed as a novel tool for phase swapping in Low Voltage Distribution Networks where the objective is to determine to which phase each load should be connected in order to reduce the ...
Bordagaray, Ana González +5 more
core +2 more sources