Results 41 to 50 of about 4,143,620 (277)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
STUDIES ON INFECTIOUS LARYNGOTRACHEITIS IN CHICKENS I. ISOLATION AND IDENTIFICATION OF INFECTIOUS LARYNGOTRACHITIS FROM SOME CHICKEN FLOCKS [PDF]
Veterinary Medical Journal - Giza, 2007 Infectious laryngotracheitis virus (ILTV) was detected in chicken laryngeal and tracheal samples from outbreaks in 4 governates in Egypt (Kalubia, Sharkia and Gharbia).
BASTAMY A +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Australian and New Zealand Journal of Public Health, 2003 Objective: The computer‐assisted telephone interviewing (CATI) method has grown rapidly in recent years as an epidemiological tool for obtaining data on health issues.
Adrian Serraglio +2 more
doaj +1 more source
Proton Conduction in Gly-X (X = Ser, Ser-Gly-Ser) and GS50
Bioengineering, 2023 In recent years, the use of biomaterials has been required from the viewpoint of biocompatibility of electronic devices. In this study, the proton conductivity of Glycyl-L-serine (Gly-Ser) was investigated to clarify the relationship between hydration and proton conduction in peptides.
Hitoki Semizo +5 more
openaire +3 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
BMC Public Health, 2020 Background Cardiovascular diseases (CVDs) and diabetes mellitus (DM) are among the leading cause of morbidity and mortality in low-and-middle-income countries (LMICs) but evidence in these contexts regarding the effectiveness of primary prevention ...
Pablo Miranda-Machado +8 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Safety & Fire Technology, 2021 Aim: The article presents a set of parameters and settings for unmanned aerial vehicles (UAV), which is crucial in the operational work of the fire brigade and its importance for the quality of the final material obtained from an RGB camera or a thermal
Maciej Zawistowski, Radosław Fellner
doaj +1 more source