Results 201 to 210 of about 543,604 (270)

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Chemical Ligation of Backbone N‐hydroxylated Peptides

Chemistry – A European Journal, EarlyView.
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio, Juan R. Del Valle   +1 more
wiley   +1 more source

[Diabetic neuropathy and its relationship with quality of life in patients with type 2 diabetes]. [PDF]

Aten Primaria
Arévalo Ramírez JR, Castañón Sánchez DL, Vargas Ordoñez OI, Camarena Velázquez HS, Aguirre García MDC, Osorio Granjeno MC.   +5 more
europepmc   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

How the hemotherapy nursing team perceives touch during the transfusion procedure. [PDF]

Rev Bras Enferm
de Azevedo Gonçalves FG, de Araújo STC, de Azevedo AL, Ferreira PBP, Torres DG, Almeida Costa FN, Doria KCF, Cabanelas KV.   +7 more
europepmc   +1 more source

Hidden Markov graphical models with state‐dependent generalized hyperbolic distributions

Canadian Journal of Statistics, EarlyView.
Abstract In this article, we develop a novel hidden Markov graphical model to investigate time‐varying interconnectedness between different financial markets. To identify conditional correlation structures under varying market conditions and accommodate shape features embedded in financial time series, we rely upon the generalized hyperbolic family of ...
Beatrice Foroni, Luca Merlo, Lea Petrella   +2 more
wiley   +1 more source

Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles. [PDF]

Protein Sci
Carosella N, Pastorello C, Waeytens J, Beniamino Y, Roncassaglia V, Serra L, Raussens V, Mileo E, Ciurli S, Zambelli B.   +9 more
europepmc   +1 more source

Tuning the Growth Pattern of Triangular Silver Nanoplates from Lateral to Vertical by Secondary Metal Addition

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
What happens, if in the synthesis of flat silver platelets, the slow deposition of silver along twinning faults is disturbed by the addition of a nobler metal? We have looked into it and found a way to fine‐tune the metal deposition in lateral and vertical direction.
Jonas Kluitmann, Andrea Csáki, Wolfgang Fritzsche, Johann Michael Köhler   +3 more
wiley   +1 more source

Effectiveness of auriculotherapy and laser acupuncture in hyperemesis gravidarum: a randomized clinical trial. [PDF]

Rev Lat Am Enfermagem
Oliva LL, Rodrigues R, Pinto KRTDF, Marcon SS, Bernardy CCF.   +4 more
europepmc   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source