Results 41 to 50 of about 193,121 (287)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

AB KOŞULLULUK POLİTİKASININ GÜNCEL ANALİZİ: “İYİ KOMŞULUK İLİŞKİLERİ VE İKİLİ İLİŞKİLERİN NORMALLEŞTİRİLMESİ” KAPSAMINDA SIRBİSTAN-KOSOVA DİYALOĞU ÜZERİNE İNCELEME

Ankara Avrupa Çalışmaları Dergisi, 2020
Bu makale, AB koşulluluk politikasını ülkelerarası meseleler ve iyi komşuluk ilişkileri çerçevesinde analiz etmekte ve Güneydoğu Avrupa (Batı Balkanlar) genişlemesi kapsamında Sırbistan-Kosova Diyaloğu özelinde tartışmaktadır.
Pınar Atakara
doaj   +1 more source

The impact of gender differences on mortality in elderly patients after hip fracture [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Hip fracture is one of the leading causes of death in elderly population. We evaluated the impact of gender differences on mortality rate in elderly patients with hip fracture. Methods. The study included all hospitalized elderly patients
Prodović Tanja T., Ristić Branko M., Vučetić Dušan D., Ignjatović-Ristić Dragana I.   +3 more
doaj   +1 more source

Multi‐Ion Doping Controlled CEI Formation in Structurally‐Stable High‐Energy Monoclinic‐Phase NASICON Cathodes for Sodium‐Ion Batteries

Advanced Functional Materials, EarlyView.
The graphical abstract illustrates the synthesis pathway, morphological feature, and thermodynamic feasibility of entropy‐engineered NASICON cathodes for sodium‐ion batteries. Abstract Overcoming the energy density limitations of sodium‐ion batteries (NIBs) requires innovative strategies to optimize cathode materials.
Sharad Dnyanu Pinjari, Vignesh Mahalingam, Purandas Mudavath, Malavika Aarayil, Tasdique Arman, Ipsita Pal, Dipan Kundu, Raghavan Ranganathan, Ashok Kumar Nanjundan, Rohit Ranganathan Gaddam   +9 more
wiley   +1 more source

Construction of the first railway in Serbia: Between corruption, diplomacy and the interests of the great powers [PDF]

Baština
This work will deal with the role of Serbian diplomacy in the construction of the first railway on Serbian territory. The Duchy was granted independence at the Berlin conference in 178, something that brough along with it the obligation to construct a ...
Timotijević Miloš D.
doaj   +1 more source

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

Advanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti, Andrea Cimolato, Noemi Gozzi, Pietro Palopoli, Luca Brugnoli, Natalija Katic Secerovic, Rebecca Gallivan, Alexander Shokurov, Carlo Menon, Johannes Weichart, Ignacio Delgado‐Martinez, Weiguo Song, Stavros Zanos, Xavier Navarro, Stanisa Raspopovic   +14 more
wiley   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

Advanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer, Sridhar Priyankha, Gopal Hema, Anouar Zerouali, Hamza Haddag, Muneerah Mogren Al Mogren, Muthuramalingam Prakash, Majdi Hochlaf   +7 more
wiley   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

"Serbian, first phase" of the supression of the epidemics in 1914 and 1915 [PDF]

Vojnosanitetski Pregled, 2018
nema
Čukić Goran
doaj   +1 more source