Results 91 to 100 of about 4,675 (249)

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

open access: yesAdvanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin   +8 more
wiley   +1 more source

MODERNIZATION OF EDUCATION: THE CAPITAL MYTH AND PROVINCIAL REALITY...

open access: yesМодернизация, инновация, развитие, 2016
The state of native education today can be compared except that of the capital alone beautiful Russian Renaissance: the facade is beautiful, the finish is presentable, glass Windows in the setting sun Shine Venetian mirror-like Shine, soft pastel the ...
T. L. Likhacheva, A. N. Kuryukin
doaj  

An Serene

open access: yes, 2012
Source: Johann Jakob Dusch: Sympathie, ein Gedicht zur Unterstützung einer unglücklich gewordenen Familie von Johann Jacob Dusch, Altona: Bülowsche Buchdruckerei, 1774.
openaire   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

A Sustainable Bio‐Based Epoxy Thermoset as a High‐Performance Alternative to BPA‐Based Resins

open access: yesAdvanced Science, EarlyView.
A rigid–flexible bio‐based epoxy network integrates soybean oil, lignin, and maleic anhydride to overcome the strength–toughness–sustainability trade‐off of conventional BPA epoxy. The thermoset delivers excellent performance as both a structural adhesive and a matrix for glass‐fabric composites, while enabling pH‐responsive degradation, environmental ...
Jiyun Qi   +4 more
wiley   +1 more source

Serenity [PDF]

open access: yesThe Permanente Journal, 2014
openaire   +2 more sources

Current Challenges of Transcription Compartmentalization Research

open access: yesAdvanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

open access: yesAdvanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang   +9 more
wiley   +1 more source

Surf et mise en tourisme à Serenity (Inde du Sud) : vers une déferlante de frictions ?

open access: yesTéoros
This contribution proposes to analyze the consequences of the promotion of surfing on the structuring of a particular tourist territory, the coastal area of Pondicherry (South India) and more specifically Serenity, a beach that has progressively become a
Anthony Goreau-Ponceaud
doaj  

A Rigid–Foldable Kirigami‐Inspired Metamorphic Mechanism With Programmable Motion Modes and Self‐Locking

open access: yesAdvanced Science, EarlyView.
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley   +1 more source

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