Results 101 to 110 of about 459,296 (269)

The contribution of pre-symptomatic infection to the transmission dynamics of COVID-2019 [version 1; peer review: 2 approved]

open access: yesWellcome Open Research, 2020
Background: Pre-symptomatic transmission can be a key determinant of the effectiveness of containment and mitigation strategies for infectious diseases, particularly if interventions rely on syndromic case finding. For COVID-19, infections in the absence
Yang Liu   +3 more
doaj   +1 more source

RV Ronald H. Brown Cruise RB0701, 21 Mar-10 Apr 2007. RAPID mooring cruise report [PDF]

open access: yes, 2008
This report describes the mooring operations conducted during RV Ronald H. Brown Cruise RB0701 conductedbetween 21 March 2007 and 10 April 2007.These mooring operations were completed as part of the United Kingdom Natural Environment Research Council ...
Baringer, M.O., Kanzow, T.
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The buffered chemostat with non-monotonic response functions [PDF]

open access: yes, 2013
We study how a particular spatial structure with a buffer impacts the number of equilibria and their stability in the chemostat model. We show that the occurrence of a buffer can allow a species to persist or on the opposite to go extinct, depending on ...
Haidar, Ihab   +2 more
core   +6 more sources

Intertrial interval effects in pavlovian serial feature positive discriminations [PDF]

open access: yesAnimal Learning & Behavior, 1999
The effects of the intertrial interval (ITI) on learning and performance in Pavlovian appetitive serial feature positive (SFP) discriminations were examined in three experiments with rats. With longer ITIs, acquisition was more rapid, and there was less transfer of the feature’s behavioral control to a separately trained target cue, suggesting that ...
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Serial persistence in individual real estate returns in the UK [PDF]

open access: yes, 2004
Persistence of property returns is a topic of perennial interest to fund managers as it suggests that choosing those properties that will perform well in the future is as simple as looking at those that performed well in the past.
Devaney, S., Lee, Stephen, Young, M.
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Influenza Transmission Dynamics in Urban Households, Managua, Nicaragua, 2012–2014

open access: yesEmerging Infectious Diseases, 2018
During August 2012–November 2014, we conducted a case ascertainment study to investigate household transmission of influenza virus in Managua, Nicaragua.
Aubree Gordon   +9 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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